Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (81-77) and Cleveland Guardians (74-84) meet Wednesday to conclude a 2-game series. First pitch from Progressive Field is set for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 2-1

SS Elly De La Cruz’s 1st career 2-homer game helped propel the Reds to an 11-7 victory over the Guardians as +109 road underdogs on Tuesday. The Reds are 1 1/2 games behind the Chicago Cubs for the final Wild Card berth.

With the loss, Cleveland fell into 3rd place in the AL Central, 1/2 game behind the Detroit Tigers. The Minnesota Twins have already clinched the division title.

Reds at Guardians projected starters

LHP Andrew Abbott vs. RHP Shane Bieber

Abbott (8-5, 3.70 ERA) makes his 21st start. He has a 1.27 WHIP, 3.7 BB/9 and 10 K/9 in 107 innings.

  • Last outing: No-decision, 4 1/3 IP, 2 ER, 4 H, 2 BB, 7 K in a 7-5 home loss Friday vs. the Pittsburgh Pirates
  • Career vs. Cleveland: 1-0, 3.60 ERA (5 IP, 2 ER), 6 H, 0 BB, 5 K in 1 start

Bieber (5-6, 3.91 ERA) makes his 21st start. He has a 1.25 WHIP, 2.5 BB/9 and 7.4 K/9 in 122 innings.

  • Last outing: No-decision, 5 IP, 4 ER, 6 H, 1 BB, 5 K in a 9-8 home win Friday vs. the Baltimore Orioles
  • Career vs. Cincinnati: 3-0, 3.51 ERA (33 1/3 IP, 13 ER), 24 H, 9 BB, 39 K in 5 starts

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Reds at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 11:08  p.m. ET.

  • Moneyline (ML): Reds +110 (bet $100 to win $110) | Guardians -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-200) | Guardians -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Reds at Guardians picks and predictions

Prediction

Reds 3, Guardians 1

Moneyline

BET REDS (+110).

The Reds are the better team and have much more to play for and they are also  the hotter team, having won 2 straight while the Guardians have lost 3 in a row. Cincinnati is also better on the road (43-34) than Cleveland is at home (41-39).

Run line/Against the spread

PASS.

I feel confident in picking the Reds to cover here but at +1.5 (-200) the line is far too risky. Bet on the moneyline and/or total instead.

Over/Under

LEAN UNDER 7.5 (-105).

The Under is 3-1 in the last 4 Cincinnati-Cleveland matchups overall and is 4-2 in Cleveland’s last 6 overall. The Under has also hit in 3 of Abbott’s last 5 starts and hit in his only career start vs. Cleveland.

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