Chicago White Sox at Toronto Blue Jays odds, picks and predictions

Analyzing Wednesday’s Chicago White Sox at Toronto Blue Jays odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (15-34) and Toronto Blue Jays (21-26) wrap up a 3-game set at Rogers Centre Wednesday. First pitch is scheduled for 7:07 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The White Sox beat the Blue Jays 5-0 as +171 road underdogs in the 2nd game of the series Tuesday as the Under (7) hit. LHP Garrett Crochet won his 4th consecutive start for the White Sox, who snapped a 4-game skid.

The Blue Jays finished with just 2 hits and were shut out for the 3rd time this season. LHP Yusei Kikuchi lost his 3rd consecutive decision for Toronto, which failed to cash as a -187 favorite.

White Sox at Blue Jays projected starters

RHP Nick Nastrini vs. RHP Chris Bassitt

Nastrini (0-2, 7.88 ERA) makes his 3rd start. The rookie has a 2.00 WHIP, 7.9 BB/9 and 9.0 K/9 in 8 innings.

  • Last start: Loss, 3 IP, 5 ER (6 R), 6 H, 5 BB, 3 K in 8-2 defeat at Philadelphia Phillies April 21
  • 2024 stats with Triple-A Charlotte: 0-4, 6.75 ERA (29 1/3 IP, 19 ER), 1.50 WHIP in 6 starts
  • Has never faced Blue Jays before

Bassitt (3-6, 5.03 ERA) makes his 10th start. He has a 1.53 WHIP, 4.3 BB/9 and 8.4 K/9 in 48 1/3 innings.

  • Last start: Loss, 5 2/3 IP, 3 ER, 5 H, 3 BB, 5 K in 4-3 home setback vs. Tampa Bay Rays Friday
  • 2024 home stats: 2-3, 4.94 ERA (27 1/3 IP, 15 ER), 1.46 WHIP in 5 starts
  • Career vs. White Sox (regular season): 3-2, 3.89 ERA (37 IP, 16 ER), 1.22 WHIP in 7 starts, including 1-0 with a 3.65 ERA (12 1/3 IP, 5 ER) last season

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White Sox at Blue Jays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:01 a.m. ET.

  • Moneyline (ML): White Sox +200 (bet $100 to win $200) | Blue Jays -250 (bet $250 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (+100) | Blue Jays -1.5 (-120)
  • Over/Under (O/U): 8.5 (O: +100 | U: -120)

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White Sox at Blue Jays picks and predictions

Prediction

Blue Jays 4, White Sox 3

Moneyline

It’s unlikely that the Blue Jays (-250) will drop 2 of 3 against the White Sox, who have the worst record in the AL. However, risking $250 to win $100 on a team that has lost 4 of 5 seems a little expensive.

PASS. Bet the RL and/or total instead.

Run line/Against the spread

While Nastrini struggled last time out, he allowed just 2 ER in his MLB debut April 15 against the Kansas City Royals (8th-best offense in MLB with 4.78 runs per game). The Blue Jays are 29th in MLB with 3.68 runs per game, so there is a chance that Nastrini could bounce back against a bottom-tier offense.

While Toronto likely wins at home with a more experienced starting pitcher, the Blue Jays have scored just 4 or fewer runs in 6 of their last 7 games — winning by 2 or more is a tough ask. We know how bad the Blue Jays offense is, but we’re not sure yet if Nastrini is actually a bad pitcher.

BET WHITE SOX +1.5 (+100).

Over/Under

The Under has hit in 10 of Chicago’s last 13 games and 8 of Toronto’s last 10. These are the 2 worst offenses in MLB this season. Nastrini’s ERA is also inflated because he’s only faced the Phillies and Royals, who have the 2nd- and 8th-highest batting averages in MLB, respectively.

BET UNDER 8.5 (-120).

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