Chicago White Sox at Minnesota Twins odds, picks and predictions

Analyzing Monday’s Chicago White Sox at Minnesota Twins odds and lines, with MLB expert picks, predictions and best bets.

The Chicago White Sox (4-6) and Minnesota Twins (6-3) renew their AL Central Division rivalry with the opener of a 3-game set Monday at Target Field. First pitch is at 2:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Twins odds and make our expert MLB picks and predictions for the best bets.

Season series: 1st meeting; Minnesota won 10-9 in 2022

The White Sox fell to the Pirates 1-0 Sunday and lost 2 of the 3 games in Pittsburgh over the weekend. The Sox are 28th in baseball, allowing just over 7 runs per game. That should improve with ace Dylan Cease on the bump Monday.

The Twins have been stingy on the scoreboard, allowing the 3rd-fewest runs per game at 2.7. They took 2 of 3 from the AL Champs Houston Astros over the weekend. OF Byron Buxton looks poised for a comeback season as he’s hitting .324 with 3 extra-base hits in his 1st 34 at-bats.

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White Sox at Twins projected starters

RHP Dylan Cease vs. RHP Kenta Maeda

Cease (1-0, 1.59 ERA) makes his 3rd start. He has a 0.71 WHIP, 4.0 BB/9 and 14.3 K/9 in 11 1/3 IP.

  • Was 2-0 and allowed just 2 H and 4 BB while fanning 15 in 16 shutout IP against the Twins last year
  • Has allowed just 3 H and 5 BB in his 2 starts this season

Maeda (0-1, 1.80 ERA) makes his 2nd start. He allowed 1 ER on 3 H and struck out 9 in 5 IP against the Miami Marlins April 4.

  • Faced the White Sox twice in 2021 and was rocked for 10 ER on 12 H and 7 BB while fanning 7 in 9 2/3 IP

White Sox at Twins odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 a.m. ET.

  • Moneyline (ML): White Sox -105 (bet $105 to win $100) | Twins -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox -1.5 (+165) | Twins +1.5 (-200)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

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White Sox at Twins picks and predictions

Prediction

White Sox 6, Twins 3

Moneyline

With the history that Cease and Maeda have against the respective teams, it’s hard not to jump at the White Sox -105. Chicago won 3 of the last 4 meetings last season, and Cease was unhittable. He has opened the season in crisp fashion if he can keep the walks to a minimum.

Take the WHITE SOX -105.

Run line/Against the spread

Seven of the last 10 meetings between the teams was decided by 2 runs or more. Three of the White Sox’s 4 wins have been by multiple runs as well. The team is wildly inconsistent, but the WHITE SOX -1.5 (+165) is worth a half-unit.

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Over/Under

The Over is 5-0 in the White Sox’s last 5 road games with the total set at 7.0-8.5. The Over is 5-0 in Chicago’s last 5 games following a loss as well. The Over is 8-2 for the White Sox this season. I wouldn’t go a full unit, but I will LEAN OVER 7.5 (-110).

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