Chicago White Sox at Los Angeles Angels odds, picks and predictions

Analyzing Monday’s Chicago White Sox at Los Angeles Angels odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (35-115) and Los Angeles Angels (60-89) open a 3-game series Monday. First pitch from Angel Stadium is set for 9:38 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox vs. Angels odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Angels won 4-3 last year

The White Sox took 2 of 3 games over the weekend against the Oakland A’s, winning a pair of 1-run games as underdogs. The Under cashed in 2 of the 3 games, and the total has gone low at a 5-2 pace in the previous 7 outings.

The Angels were swept by the visiting Houston Astros over the weekend, losing all 3 games by exactly 2 runs apiece. The Under cashed in 2 of 3 games, too, although the Over is on a 5-2-1 pace in the past 8 outings.

White Sox at Angels projected starters

RHP Jonathan Cannon vs. LHP Reid Detmers

Cannon (3-10, 4.56 ERA) makes his 19th start and 21st appearance. He has a 1.40 WHIP, 3.6 BB/9 and 6.2 K/9 in 106 2/3 IP.

  • Last start: Loss, 5 1/3 IP, 3 ER, 7 H, 1 BB, 4 K in 5-0 home setback vs. Cleveland Guardians Tuesday
  • 2024 road splits: 2-5, 4.94 ERA, 47 1/3 IP, 26 ER, 7 HR, 1.48 WHIP, .310 opponents’ batting average (OBA), 12 BB, 34 K in 9 starts
  • Last 7 games: 2-5, 5.40 ERA, 36 2/3 IP, 22 ER, 16 BB, 28 K, 1.64 WHIP
  • Has never faced Angels

Detmers (4-6, 5.64 ERA) makes his 15th start. He has a 1.40 WHIP, 3.7 BB/9 and 10.6 K/9 in 75 IP.

  • Last start: Win, 6 IP, 2 ER, 5 H (1 HR), 2 BB, 8 K in 6-2 road victory vs. Minnesota Twins Sept. 9
  • 2024 home splits: 1-4, 5.77 ERA, 39 IP, 25 ER, 4 HR, 1.38 WHIP, .263 OBA, 14 BB, 49 K in 7 starts
  • Last 7 games: 1-3, 7.27 ERA, 34 2/3 IP, 28 ER, 17 BB, 44 K, 1.62 WHIP
  • Career vs. White Sox: No-decision, 7 IP, 1 ER, 2 H (1 solo HR), 2 BB, 10 K in 1 start, a 2-1 home victory June 26, 2023

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Angels odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 9:34 a.m. ET.

  • Moneyline (ML): White Sox +155 (bet $100 to win $155) | Angels -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-140) | Angels -1.5 (+115)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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White Sox at Angels picks and predictions

Prediction

White Sox 6, Angels 5

Moneyline

The WHITE SOX (+155) are worth playing as moderate underdogs in the series opener with the Angels (-190) in this battle of eliminated teams.

Chicago comes in with a little bit of momentum, winning 2 in a row. The White Sox are looking for their 1st 3-game winning streak since June 27-29.

You can’t back the Angels (-190), risking nearly twice your potential return, as they enter this one on a 5-game skid while losing 7 of the previous 8 outings.

Run line/Against the spread

If you’re a little more conservative and just can’t bring yourself to play Chicago straight up, WHITE SOX +1.5 (-140) is not priced out of line. Chicago is a respectable 4-6 on the run line as an underdog in the past 10 games while winning all 4 of those games outright.

Over/Under

OVER 8 (-115) might be the best play on the board in this series opener.

The Over is on a 5-2-1 run across the past 8 games for the Angels while splitting 5-5 across the past 10 outings at home.

For the White Sox, the O/U has split 2-2 in the past 4 outings, while the Over is 5-2 in the previous 7 contests on the road.

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