Chicago White Sox at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Chicago White Sox at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (61-59) take on the Cleveland Guardians (64-55) Saturday in the 2nd game of a 3-game set at Progressive Field. First pitch is set for 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the White Sox vs. Guardians odds with MLB picks and predictions.

Season series: Guardians lead 9-5

The tides keep turning for the White Sox, who have dropped 3 in a row after a 5-game win streak. They are 26-26 within the division and 3½ games back of the 1st-place Guardians. If there was a must-win game in August, this is it.

The Guardians took care of business 5-2 in Friday’s opener behind RHP Triston McKenzie’s career-high 14 strikeouts. They’re in a good position with their ace on the hill Saturday. Cleveland has won 10 of 13 and boast a 32-24 home record.

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White Sox at Guardians projected starters

RHP Johnny Cueto vs. RHP Shane Bieber

Cueto (5-5, 2.78 ERA) makes his 17th start and 18th appearance. He has a 1.20 WHIP, 2.0 BB/9 and 5.8 K/9 in 110 IP.

  • Allowed 1 ER on 6 H and 1 BB with 3 K in 8 IP last time out to beat the visiting Houston Astros 4-2 Monday
  • No-decision at home against Cleveland July 23 after allowing 3 ER on 8 H and 1 BB with 0 K in 7 IP

Bieber (8-6, 3.18 ERA) makes his 23rd start. He has a 1.10 WHIP, 1.9 BB/9 and 9.1 K/9 in 138 2/3 IP.

  • Owns a 3.21 ERA (47 2/3 IP, 17 ER) and 5-2 record over the last 7 starts
  • Allowed 6 ER in 6 IP in 6-3 loss at the White Sox July 24 but held them to 2 ER in 15 IP, including complete-game victory, in other 2 starts against them this year, both wins

White Sox at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:38 p.m. ET.

  • Money line (ML): White Sox +145 (bet $100 to win $145) | Guardians -180 (bet $180 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-155) | Guardians -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -107 | U: -115)

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White Sox at Guardians picks and predictions

Prediction

Guardians 4, White Sox 2

Money line

It’s possible that Chicago steals this one as Cueto was awesome against Houston last time out. However, I think Bieber holds it down at home. Cleveland has scored 4 or more runs in 7 of 9 games, and that’s what it will take to get it done Saturday.

Instead of paying the -180 juice, let’s go with GUARDIANS TOTAL RUNS OVER 3.5 (-150).

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Run line/Against the spread

I’m not confident enough in the Guardians offense, despite picking a 4-2 win to throw down on the RL. One way we can go is to read into Bieber’s last 2 starts at home against the White Sox. He allowed 3 hits in 9 innings (July 12) and 4 hits in 6 innings (April 20).

So, let’s go with WHITE SOX UNDER 4.5 HITS FIRST 5 INNINGS (-145) for a HALF UNIT.

Over/Under

The Over is just 3-7 in the Guardians’ last 10 games, and they’ve won 7 of those.

The Under is 4-0 in the last 4 meetings between these teams in Cleveland.

The Under is 5-0 in Bieber’s last 5 home starts when the total was between 7.0-8.5.

UNDER 7.5 (-115) looks good Saturday.

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