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The Chicago White Sox (24-63) and Cleveland Guardians (53-30) play the middle contest of a 3-game series Wednesday. First pitch from Progressive Field is scheduled for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Guardians odds and make our expert MLB picks and predictions for the best bets.
Season series: Tied 4-4
The Guardians walked it off with a sacrifice fly from pinch-hitter Bo Naylor in the bottom of the 9th inning for a 7-6 win over the last-place White Sox in a wild seesaw battle in Tuesday’s series opener. Despite the win, Cleveland is just 4-4 this season against Chicago.
Cleveland is 13-9 inside the AL Central, while going only 2-4 in the past 6 tries inside the division. The Under has a 12-10 edge in 22 divisional matchups.
Guardians RHP Gavin Williams (elbow) was reinstated from the 60-day injured list after recovering from right elbow discomfort and will start Wednesday. He posted a 10:2 K:BB ratio in his final 2 rehab starts for Triple-A Columbus after a sluggish start to his assignment.
Chicago has dropped back-to-back road games after winning 3 in a row from June 27-29. The White Sox are just 3-14 in the past 17 road outings. The Over has cashed in 3 straight, with the offense averaging 7.0 runs per game (RPG), while allowing 5.0 RPG in the span.
White Sox at Guardians projected starters
RHP Erick Fedde vs. RHP Gavin Williams
Fedde (5-3, 3.23 ERA) makes his 18th start. He has a 1.14 WHIP, 2.2 BB/9 and 8.2 K/9 in 100 1/3 IP.
- Last start: Loss, 6 IP, 4 ER, 5 H (1 HR), 1 BB, 5 K in 4-0 home loss vs. Los Angeles Dodgers June 26
- 2024 road splits: 1-2, 4.47 ERA (56 1/3 IP, 28 ER), 1.31 WHIP, .257 opponents’ batting average (OBA), 7 HR, 17 BB, 50 K in 10 starts
- 2024 vs. Guardians: 1-0, 3.27 ERA (11 IP, 5 R – 4 ER), 3 HR, 3 BB, 6 K in 2 starts
- Career vs. Guardians: 1-0, 2.77 ERA (13 IP, 5 R – 4 ER), 1.08 WHIP, 3 HR, 4 BB, 6 K in 3 appearances (2 starts)
Williams makes his 1st start of 2024. He was 3-5, 3.29 ERA (82 IP, 30 ER), 8 HR, 37 BB, 81 K in 16 starts in 2023
- Last start: Win, 6 IP, 1 ER, 4 H, 2 BB, 8 K in 9-2 home win vs. Texas Rangers Sept. 17, 2023
- 2023 home splits: 3-3, 3.74 ERA (53 IP, 22 ER), 1.32 WHIP, .234 OBA, 23 BB, 53 K in 10 starts
- Has never faced White Sox
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
White Sox at Guardians odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 10:42 p.m. ET.
- Moneyline (ML): White Sox +145 (bet $100 to win $145) | Guardians -175 (bet $175 to win $100)
- Run line (RL)/Against the spread (ATS): White Sox +1.5 (+140) | Guardians -1.5 (+115)
- Over/Under (O/U): 8.5 (O: -105 | U: -115)
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White Sox at Guardians picks and predictions
Prediction
White Sox 4, Guardians 3
Moneyline
The WHITE SOX (+145) aren’t a bad play as a moderate underdog against the Guardians (-175), especially since Williams could be a little rusty after a lengthy layoff due to his elbow ailment.
The ChiSox have handled the Guardians pretty well this season, splitting 8 games to date. Tuesday’s series opener was a seesaw affair, too, and it easily could have gone Chicago’s way.
Run line/Against the spread
The WHITE SOX +1.5 (-140) aren’t priced out of line, if you’d like a little insurance, and you just can’t bring yourself to back Chicago straight up as the moderate underdog.
The White Sox have dropped back-to-back games, but both losses are by a single run. Chicago is a respectable 6-3 on the run line in the past 9 as an underdog, including outright wins in 3 of the outings.
Over/Under
UNDER 8.5 (-115) is the lean in Wednesday’s battle at Progressive Field.
The Over cashed in a wild affair Tuesday, but Fedde has been pretty effective, and he should be able to help keep score down. And while the Over is 3-0 in the past 3 for the White Sox, the Under is still 10-4 across the past 14 outings, including Fedde’s past 2 starts.
For the Guardians, the Over is 3-1 in the past 4 games, but the Over-Under has split 5-5-1 in the past 11 outings since June 21. The Over-Under is 4-4 in the 8 meetings these season, too.
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