The Chicago White Sox (20-30) and Cleveland Guardians (21-27) play the finale of a 3-game set at Progressive Field Wednesday. First pitch is at 1:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Guardians odds and make our expert MLB picks and predictions for the best bets.
Season series: White Sox lead 3-2
The White Sox took Game 2 of the series Tuesday 4-2. C Yasmany Grandal homered, and RHP Dylan Cease allowed 2 ER over 6 innings. The White Sox are now 7-3 over the last 10 games. Chicago is 10-8 against the AL Central and sits 5.5 games back in the division despite being 10 games under .500.
The Guardians have lost 6 of their last 8 games, and they managed 4 runs in a game just twice in that stretch. They are also just 2-5 in the last 7 home games against the White Sox. Cleveland is 12-18 over the last 30 games, but because it plays in arguably the weakest division in baseball, it sits 3.5 games out of 1st place.
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White Sox at Guardians projected starters
RHP Michael Kopech vs. RHP Cal Quantrill
Kopech (2-4, 4.83 ERA) makes his 10th start. He has a 1.33 WHIP, 5.0 BB/9 and 9.1 K/9 in 50 1/3 innings.
- Dominated the Kansas City Royals in last start Friday: 8 IP, 0 ER, 1 H, 0 BB, 10 K
- 2 career starts vs. Cleveland: 0-0, 0 ER and 11 K in 8 IP
Quantrill (2-2, 4.06 ERA) makes his 10th start. He has a 1.31 WHIP, 2.6 BB/9 and 5.1 K/9 in 51 innings.
- Last start: No-decision, 5 2/3 IP, 3 ER, 6 H, 0 BB, 6 K, against the New York Mets Friday
- Last 5 starts vs. White Sox: 2-1, 3.67 ERA, 1.33 WHIP, 21 K in 27 IP
White Sox at Guardians odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:16 a.m. ET.
- Moneyline (ML): White Sox +115 (bet $100 to win $115) | Guardians -135 (bet $135 to win $100)
- Run line (RL)/Against the spread (ATS): White Sox +1.5 (-175) | Guardians -1.5 (+145)
- Over/Under (O/U): 8 (O: -105 | U: -115)
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White Sox at Guardians picks and predictions
Prediction
White Sox 4, Guardians 2
Moneyline
We have gone 5-1 on picks in this series, and there looks to be value in this afternoon affair. I like the White Sox here because of Cleveland’s inability to score runs and because Kopech is coming off the best start of his career.
Kopech has always been a guy that threw hard, but you could count on him to walk 2 hitters a start, but he has not done so in 2 of his last 3 starts. We’ll need him to get 2 outs into the 6th inning, and he has gone 6 innings in 3 of 4 starts and did so in his last one against Cleveland.
Take MICHAEL KOPECH OVER 16.5 OUTS RECORDED (-110).
Run line/Against the spread
Each game has been decided by more than 1 run between these clubs this year, and they haven’t had a 1-run game in the last 12 meetings. So we’ll use this as a de facto moneyline bet and LEAN WHITE SOX -1.5 (+190) for a chance to nearly double up.
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Over/Under
The wind is blowing in at 11 mph on a 72-degree day for this Wednesday matinee. The Under is 7-1 in the last 8 meetings between these teams in Cleveland. The Under is 7-0-1 in the last 8 for Cleveland against a team under .500. The Under has cashed in Chicago’s last 6 games overall and its last 4 outings following a win.
Only go a HALF-UNIT here because things could get messy on getaway day, but take the UNDER 8 (-115).
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