The Chicago White Sox (47-72) and Chicago Cubs (61-57) open up a 2-game set at Wrigley Field Tuesday. First pitch is at 8:05 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the White Sox vs. Cubs odds and make our expert MLB picks and predictions for the best bets.
Season series: Cubs lead 2-0
The White Sox’s down year continues as they have dropped 4 of their last 5 games and are just 6-14 over the last 20 games. The Sox also haven’t enjoyed interleague play much at 11-21 and are 14 1/2 games out in the AL Central with little shot at the postseason.
The Cubs are buzzin’. They are 14-6 and 20-10 over the last 20 and 30 games, respectively. They sit just 3 1/2 games behind the Milwaukee Brewers in the NL Central. The Cubbies are 20-18 in interleague play this season.
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White Sox at Cubs projected starters
RHP Touki Toussaint vs. RHP Kyle Hendricks
Toussaint (1-5, 4.27 ERA) makes his 8th start and 12th appearance. He has a 1.40 WHIP, 6.2 BB/9 and 9.1 K/9 in 46 1/3 innings with the White Sox and the Cleveland Guardians.
- Last start: Loss, 5 IP, 4 ER, 6 H, 5 BB, 9 K last Tuesday against New York Yankees
- 2023 home/road splits: 0-3, 5.47 ERA, 1.60 WHIP, 8.5 K/9 in 4 starts and 2 relief appearances on the road vs. 1-2, 2.70 ERA, 1.15 WHIP, 9.9 K/9 in 3 starts and 2 relief appearances at home
Hendricks (4-6, 3.96 ERA) makes his 16th start. He has a 1.12 WHIP, 1.5 BB/9 and 5.9 K/9 in 86 1/3 innings.
- Last start: No-decision, 5 IP, 2 ER, 5 H, 2 BB, 6 K Wednesday against New York Mets
- Last 5 starts vs. White Sox: 1-3, 6.43 ERA, 1.43 WHIP, 20 K in 28 IP
White Sox at Cubs odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:23 a.m. ET.
- Moneyline (ML): White Sox +140 (bet $100 to win $140) | Cubs -165 (bet $165 to win $100)
- Run line (RL)/Against the spread (ATS): White Sox +1.5 (-140) | Cubs -1.5 (+115)
- Over/Under (O/U): 8.5 (O: -115 | U: -105)
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White Sox at Cubs picks and predictions
Prediction
Cubs 6, White Sox 3
Moneyline
The Cubs won the first 2 games of the season series 10-7 and 7-3 in late July at Guaranteed Rate Field. The Baby Bears have taken 2 of 3 games from the Toronto Blue Jays and Atlanta Braves over their last 3 series, so they have beaten some impressive teams, although they did drop 2 of 3 games to the New York Mets between those series.
The Cubs aren’t as heavy favorites as I would expect, and I would consider taking them at -165. I’m looking a little bigger, though. Head to the Win/Total section and take the CUBS AND OVER 5.5 (+105) for a plus-money payout.
Run line/Against the spread
The Cubs are 32-28 on the RL at home, but I’d want a little more than +115 to pick them on a multi-run win here. We’re already getting +105 on the Cubs and Over 5.5 so if this were to swell up to +130 or more I’d throw it down.
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Over/Under
The White Sox are 4-6 O/U over the last 10 games, and the Cubs are 5-5. Both of the previous games went Over and the Over is 6-3-1 in the last 10 meetings in this series. Toussaint has allowed 4 ER or more in 4 of his last 5 starts, and Hendricks has allowed 9 ER in 9 innings over his last 2 starts.
I like the OVER 8.5 (-115).
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