Chicago Cubs at St. Louis Cardinals odds, picks and predictions

Analyzing Wednesday’s Chicago Cubs at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (41-61) and St. Louis Cardinals (55-48) resume their 3-game series at Busch Stadium Wednesday. First pitch is scheduled for 7:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Cardinals odds with MLB picks and predictions.

Season series: Cardinals lead 5-4

Despite keeping C Willson Contreras and LF Ian Happ at the end of the trade deadline the Cubs were unable to score in their 2nd straight game, losing 6-0.

The Cardinals took an early lead and put the game away thanks to home runs from 1B Paul Goldschmidt, RF Dylan Carlson, and 3B Nolan Arenado. The Cardinals, buyers at the deadline, are now 2 games behind the Milwaukee Brewers and will try to use their momentum to close the gap.

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Cubs at Cardinals projected starters

LHP Justin Steele vs. RHP Miles Mikolas

Steele (4-7, 3.86 ERA) will make his 20th start. He has posted a 1.42 WHIP, 4.2 BB/9 and 8.6 K/9 in 91 IP.

  • Last start vs St. Louis: No-decision in 5-3 loss June 5 in Chicago with 7 IP, 7 H, 1 ER, 3 BB and 1 K
  • Has given up 1 run or less in 4 of his past 5 starts

Mikolas (8-8, 2.86 ERA) will make his 22nd start. He has a .99 WHIP, 1.8 BB/9 and 6.8 K/9 in 132 1/3 IP.

  • 3-3 in the month of July with a 3.58 ERA and a .272 opponent OBP
  • Last start: 7 IP, 6 H, 2 ER, and 4 K in a 6-2 win Friday vs. the Washington Nationals

Cubs at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:39 a.m. ET.

  • Money line: Cubs +140 (bet $100 to win $140) | Cardinals -180 (bet $180 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-145) | Cardinals -1.5 (+120)
  • Over/Under (O/U): 8.5 (O: +100 | U: -125)

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Cubs at Cardinals picks and predictions

Prediction

Cardinals 5, Cubs 3

Money line

Cardinals RHP Miles Mikolas is 4-2 at home this season with an opponent batting average of .192 vs .241 in away games.

Mikolas also throws more efficiently posting a 5.1 strikeout to walk ratio vs 3.0 away. That being said, the juice is still strong. A more practical bet is CARDINALS 1st 5 INNING WINNER (-118).

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Run line/Against the spread

St. Louis is the 3rd best team in MLB at covering when they are the home favorite. The downside is 3rd best in MLB means just 51% ATS. The Cubs still have a majority of their roster that beat these Cardinals 4 out of 9 times.  AVOID.

Over/Under

Every trend points to the UNDER 8.5 (-125).

St. Louis hits the Under 10 of the last 13 games against a left-handed pitcher. They also go Under 6 of the last 8 games when their opponent scores 2 or fewer in their last game.

The Cubs have gone Under 5 of the 6 times after a loss, and they are 7-1 overall in their last 8 games.

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