Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Thursday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The Chicago Cubs (40-57) and San Francisco Giants (48-50) meet Thursday for the opener of a 4-game series. First pitch from Oracle Park in San Francisco is scheduled for 9:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Giants odds with MLB picks and predictions.

Season series: First meeting of the season. Giants won the season series 6-1 in 2021.

The Cubs have won 6 straight games, outscoring the opposition 35-13. The win streak comes after a 9-game skid from July 7-16.

The Giants enter on a 7-game slide, all on the road, last winning July 17 at home against the Milwaukee Brewers. San Francisco has won 5 of its last 6 at Oracle Park.

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Cubs at Giants projected starters

LHP Justin Steele vs. LHP Alex Wood

Steele (4-6, 4.02 ERA) makes his 19th start. He has a 1.42 WHIP, 4.2 BB/9 and 8.3 K/9 through 87 1/3 IP.

  • Is just 1-2 with a 5.23 ERA and .257 opponent batting average with 39 K across 32 2/3 IP over 7 road outings.
  • Has a solid 1-1 record with a 2.55 ERA and .188 opponent BA across 3 starts in July, his lowest marks in either of those categories in any month this season.

Wood (6-8, 4.21 ERA) makes his 20th start. He has a 1.26 WHIP, 2.2 BB/9 and 9.2 K/9 through 94 IP.

  • Is 2-3 with a 3.95 ERA and 40 K across 41 IP over 8 home starts.
  • Has allowed just 3 HR at home vs. 7 HR through 53 IP across 11 road outings.

Cubs at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:28 a.m. ET.

  • Money line (ML): Cubs +122 (bet $100 to win $122) | Giants -150 (bet $150 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-175) | Giants -1.5 (+140)
  • Over/Under (O/U): 7.5 (O: -125 | U: +100)

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Cubs at Giants picks and predictions

Prediction

Giants 6, Cubs 4

Money line

The GIANTS -1.5 (+140) are a bit of a risky play based on the fact they’re on a major losing skid while the Cubs have been hot. However, San Francisco is not only 5-1 across its last 6 home games, but it outscored the opposition 38-17 during that span.

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Run line/Against the spread

The GIANTS -1.5 (+140) are the lean here given the juicy payout. There is definitely some risk considering the opposing streaks these two teams have been on of late, but San Francisco should get to Steele on the road in its return home from a road trip.

Over/Under

The OVER 7.5 (-125) is the lean, as the wind will be blowing out to the left-center field power alley. With a pair of left-handed hurlers on the bump, right-handed hitters have to be licking their collective chops.

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