The Chicago Cubs (10-18) face the San Diego Padres (19-11) Tuesday for the 2nd of their 3-game set at Petco Park with the first pitch scheduled for 9:40 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cubs vs. Padres odds with MLB picks and predictions.
Chicago won the series opener 6-0 Monday behind an 8 2/3 IP-gem by SP Kyle Hendricks, who struck out 7 and gave up just 3 H and 1 BB.
Cubs at Padres projected starters
LHP Wade Miley vs. RHP Mike Clevinger
Miley is making his 2022 and Cubs debut Tuesday. He was 12-7 in 2021 while pitching for the Cincinnati Reds with a 3.37 ERA (163 IP, 61 ER), 1.33 WHIP, 2.8 BB/9 and 6.9 K/9 in 28 starts.
- 2021 vs. Padres: No decision in 1 start, Cincy’s 6-4 loss in mid-June with 7 IP, 2 ER, 4 H, 2 HR, 2 BB and 5 K.
Clevinger (0-0, 5.79 ERA) got a no decision in his season debut Wednesday with 4 2/3 IP, 3 ER, 4 H, 3 BB and 4 K in San Diego’s 6-4 road win at the Cleveland Guardians.
Cubs at Padres odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:17 p.m. ET.
- Money line (ML): Cubs +135 (bet $100 to win $135) | Padres -170 (bet $170 to win $100)
- Run line (RL)/Against the spread (ATS): Cubs +1.5 (-165) | Padres -1.5 (+133)
- Over/Under (O/U): 6.5 (O: -125 | U: +100)
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Cubs at Padres picks and predictions
Prediction
Padres 3, Cubs 2
Money line
LEAN PADRES (-170) since they are 8-3 overall vs. left-handed starters and San Diego has been steamed up by sharp line movement from around a -140 opening ML favorite, according to VegasInsider.com.
San Diego’s lineup ranks in the top-10 against left-handed pitching in hard-hit rate (8th), wRC+ (9th), wOBA (9th) and BB/K rate (5th), per FanGraphs.
However, it’s only a LEAN to the PADRES (-170) because this ML is pricey considering Chicago’s bullpen has better pitching peripherals and Clevinger is still working his way back from an injury that kept him sidelined in 2021.
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Run line/Against the spread
PASS because the Padres -1.5 (+133) are just 4-6 RL as home favorites and haven’t scored more than 3 runs in their last 5 games and the Cubs +1.5 (-165) are 6-5 RL as road underdogs.
Over/Under
LEAN UNDER 6.5 (+100) only because we are getting to the party late on the total since it opened at 7.5, but has been steamed down by a flood of sharp money.
But, Cubs-Padres is 1-5-1 O/U in their last 7 meetings, Petco Park is a pitcher-friendly ballpark and the weather forecast is predicting nearly 13 mph winds blowing in from right-center field.
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