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The Cincinnati Reds (52-55) welcome the Chicago Cubs (51-58) to Great American Ball Park Wednesday for the finale of their 3-game series. First pitch is set for 7:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Reds odds and make our expert MLB picks and predictions for the best bets.
Season series: Reds lead 7-2
The Reds beat the Cubs 6-3 Tuesday and 7-1 Monday.
Those back-to-back victories came following a 2-game losing streak. Cincinnati has won 5 of its last 7 games though. It is 27-28 at home. The Reds, who sit 4th in the NL Central, are 59-48 against the spread (ATS) and are 6-1 ATS over their last 7.
The Cubs are the exact opposite, having lost the last 2 games after 2 straight wins. Chicago is 2-5 over its last 7 games, scoring 3 or fewer in every loss. The Cubs are 24-33 on the road and 3-5 in their last 8 away games.
Cubs at Reds projected starters
RHP Kyle Hendricks vs. LHP Nick Lodolo
Hendricks (2-9, 6.95 ERA) makes his 15th start. He has a 1.49 WHIP, 2.7 BB/9 and 6.3 K/9 in 80 1/3 IP.
- Last start: No-decision, 5 IP, 6 R, 8 H, 0 BB, 4 K in 6-0 road loss to the Kansas City Royals Friday
- 2024 away splits: 1-5, 7.49 ERA (45 2/3 IP, 38 ER), 1.45 WHIP, 11 HR, 5.3 K/9 in 10 appearances (8 starts)
- Career vs. Reds: 8-6, 4.26 ERA (139 1/3 IP, 66 ER), 1.31 WHIP, 7.9 K/9 in 26 appearances (24 starts)
Lodolo (8-3, 3.45 ERA) makes his 17th start. He has a 1.11 WHIP, 2.6 BB/9 and 9.3 K/9 in 91 1/3 IP.
- Last start: No-decision, 6 2/3 IP, 2 R, 5 H, 1 BB, 5 K in 3-2 road win over the Tampa Bay Rays Friday
- 2024 home splits: 4-2, 4.05 ERA (46 2/3 IP, 21 ER), 1.39 WHIP, 6 HR, 8.3 K/9 in 9 starts
- Career vs. Cubs: 2-1, 3.32 ERA (21 2/3 IP, 8 ER), 1.48 WHIP, 8.7 K/9 in 4 starts
Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.
Cubs at Reds odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:46 a.m. ET.
- Moneyline (ML): Cubs +126 (bet $100 to win $126) | Reds -148 (bet $148 to win $100)
- Run line (RL)/Against the spread (ATS): Cubs +1.5 (-162) | Reds -1.5 (+134)
- Over/Under (O/U): 9.5 (O: +100 | U: -122)
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Cubs at Reds picks and predictions
Prediction
Reds 6, Cubs 3
Moneyline
BET REDS (-148).
The Reds have dominated the season series against Chicago, and the Cubs offense has been nonexistent as of late. They have scored 3 or fewer runs in 9 of their last 11 games and have allowed 5 or more runs in 4 of those.
The Reds have scored 4 or more runs in 6 of their last 10 and have won 5 of their last 6 games at home. Cincinnati has also won consistently with Lodolo on the mound, coming out on top in 11 of his 16 appearances. It has won 7 of his last 10 starts.
Considering those trends, take REDS (-148).
Run line/Against the spread
PASS.
The Reds could be worth a play on the run line, but the better value is on the more expensive moneyline play. The Cubs are too risky and too expensive to consider as a run-line underdog.
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Over/Under
BET UNDER 9.5 (-122).
Both teams are trending toward the Under.
The Cubs have gone Under in 2 straight games and in 9 of their last 11. Chicago is 45-60-4 O/U on the season. Its offense has struggled, and there’s no reason to think it’ll perform well Wednesday.
The Reds have gone Under in 5 straight games and in 7 of their last 8, allowing 4 or fewer in 7 straight and 2 or fewer in 3 of their last 5. Couple all that together and take UNDER 9.5 (-122).
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