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The Chicago Cubs (48-51) and the Chicago White Sox (41-60) open a 2-game interleague series Tuesday at Guaranteed Rate Field in Chicago. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.
Season series: First meeting; White Sox won 3-1 in 2022
The Cubs have won 3 straight games, and 5 of the last 6 outings, all at home. The Over is on a 10-1-1 run in the past 12 games overall for the Cubbies, too. In interleague play, the Cubs are 16-17 so far this season.
The White Sox have dropped 3 straight games, and 5 of the last 6. Chicago has scored 44 total runs across the past 11 games, or 4.0 runs per game (RPG). The Under is on a 10-5 run across the previous 15 contests. In interleague play, the Pale Hose have managed an 11-16 mark in ’23.
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Cubs at White Sox projected starters
RHP Kyle Hendricks vs. RHP Michael Kopech
Hendricks (3-4, 3.38 ERA) makes his 12th start. He has a 1.06 WHIP, 1.4 BB/9 and 5.9 K/9 in 64 innings.
- Last start: No-decision, 6 IP, 1 ER, 5 H, 0 BB, 5 K in an 8-3 home win vs. the Washington Nationals last Wednesday
- 2023 road splits: 2-1, 2.53 ERA (32 IP, 9 ER – 3 HR), .186 opponent batting average (OBA) in 5 starts
Kopech (4-8, 4.29 ERA) makes his 19th start. He has a 1.39 WHIP, 5.6 BB/9 and 9.9 K/9 in 92 1/3 innings.
- Last start: Win, 5 2/3 IP, 1 ER, 2 H, 4 BB, 5 K in a 6-2 road win vs. the New York Mets Thursday
- 2023 home splits: 1-4, 4.07 ERA (48 2/3 IP, 22 ER – 11 HR), .195 OBA in 9 starts
Cubs at White Sox odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:49 a.m. ET.
- Moneyline (ML): Cubs -110 (bet $110 to win $100) | White Sox -110 (bet $110 to win $100)
- Run line (RL)/Against the spread (ATS): Cubs -1.5 (+150) | White Sox +1.5 (-185)
- Over/Under (O/U): 9 (O: -115 | U: -105)
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Cubs at White Sox picks and predictions
Prediction
Cubs 4, White Sox 3
Moneyline
The CUBS (-110) are a solid play behind Hendricks in this interleague game. While the White Sox (-110) have dominated this series in recent years, going 8-2 in the last 10 meetings, the Cubbies are playing much better baseball this season.
The ChiSox have struggled mightily, especially in interleague play, winning just 5 of the last 14 against the National League.
Run line/Against the spread
The White Sox +1.5 (-185) aren’t worth pursuing on the run line, if you simply want a little bit of insurance, and you just cannot trust the ChiSox straight up.
If anything, the Cubs -1.5 (+150) would be worth the play. In the last 8 wins for the Cubs, Chicago has won by 2 or more runs in 7 of the outings. Still, with the way the Sox have handled the Cubbies over the years, it’s just too risky.
PASS.
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Over/Under
UNDER 9 (-105) is worth a look, although you’ll be going against some big-time trends on the Cubs side.
The Over has cashed at a 9-2-1 clip across the last 12 games for the Cubs. However, the Under has hit in 10 of the last 15 games for the White Sox, while going 6-0-1 in Kopech’s previous 7 starts.
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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