The Chargers had their final practice ahead of the Week 2 game against the Titans this weekend.
Los Angeles is set to be without four players, most notably Austin Ekeler, who is doubtful with an ankle injury.
Ekeler is dealing with what Brandon Staley is calling an “ankle sprain,” which he sustained in last Sunday’s loss to the Dolphins.
Without Ekeler, Joshua Kelley will fill in as the primary back. In Week 1, Kelley ran for 91 yards on 16 carries.
Isaiah Spiller and Elijah Dotson are the other two backs on the 53-man roster.
L.A. will also likely be without Eric Kendricks, Daiyan Henley and Chris Rumph, who are listed as doubtful.
Without Kendricks, Kenneth Murray will wear the green dot and be the primary defensive play-caller, Staley said.
Furthermore, Joey Bosa is questionable for Week 2. After not practicing on Wednesday and Thursday, Bosa was a limited participant on Friday.
Staley said he will be a game-time decision.