Carolina Panthers at Buffalo Bills odds, picks and predictions

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The Buffalo Bills (1-1) welcome the Carolina Panthers (0-2) to Highmark Stadium Saturday for the final week of preseason. Kickoff is set for 1 p.m. ET. Below, we analyze FanDuel Sportsbook’s lines around the Panthers vs. Bills odds, and make our expert NFL picks and predictions.

The Bills lost to the Chicago Bears 33-6 in Week 1 of the preseason, failing to cover as 3-point home favorites. They did bounce back and beat the Pittsburgh Steelers 9-3 on the road Saturday, closing as 2.5-point underdogs. Buffalo is 1-1 against the spread (ATS) and 1-1 O/U. QB Josh Allen has only played 1 drive, completing 2 of 3 passes for 22 yards.

The Panthers have lost both preseason games, dropping the first battle 17-3 to the New England Patriots on the road and the second one 15-12 to the visiting New York Jets. Carolina failed to cover in both, closing as a 6.5-point underdog in the opener and a 1.5-point favorite Aug. 17. QB Bryce Young has yet to attempt a pass in the preseason, so he might see a drive Saturday.

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Panthers at Bills odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:59 a.m. ET.

Moneyline (ML): Panthers -230 (bet $230 to win $100) | Bills +190 (bet $100 to win $190)
Against the spread: Panthers -4.5 (-115) | Bills +4.5 (-105)
Over/Under (O/U): 31.5 (O: -105 | U: -115)

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Panthers at Bills picks and predictions

Prediction

Panthers 17, Bills 13

Moneyline

PASS.

There’s not much value here. The Panthers (-230) haven’t shown enough to be heavy favorites, and paying more than twice your potential return in a preseason game is far too risky.

Against the spread

BET BILLS +4.5 (-105).

The home underdog is the best play here. The Bills are coming off a win in which their defense allowed just 3 points to the Steelers. While they did allow 33 the first week, 20 of those were in the 4th quarter, so their defense held strong for most of the game.

The Panthers haven’t got much of anything going in the preseason, scoring a combined 15 points while allowing 32. They have lost both and failed to cover both. With that in mind, take the underdog here, and back BILLS +4.5 (-105).

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Over/Under

BET UNDER 31.5 (-115).

The Panthers are 0-2 O/U, having scored 12 or fewer points in both games. They likely won’t play Young much, and outside of him, their skill players lack the ability to create that offensive magic. They totaled 156 total yards against the Jets.

The Bills have yet to score double digits as well and only went Over when they allowed 33 points to Chicago in Week 1. Considering those trends for both sides and in the preseason in general, back UNDER 31.5 (-115).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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