Buffalo Bills at Miami Dolphins odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at Miami Dolphins odds and lines, with expert NFL picks, predictions and best bets.

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The Buffalo Bills (2-0) head to Hard Rock Stadium Sunday to take on the Miami Dolphins (2-0) in an early season divisional matchup to determine who will stay unbeaten. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Bills vs. Dolphins odds, and make our expert NFL picks and predictions.

The Bills are coming off a massive 41-7 Monday night victory over the Tennessee Titans. QB Josh Allen had another MVP-caliber game throwing for 317 yards and 4 TDs, hitting on 26 of 38 attempts. His top target was WR Stefon Diggs, who had 12 receptions for 148 yards and 3 TDs. Allen spread the ball around the offense with 8 players having at least 1 reception. The Bills defense played phenomenal as well, forcing 4 turnovers and holding the Titans to only 187 total yards.

The Bills have looked unstoppable in 2 games which is why Buffalo is the early season Super Bowl favorite.

Miami won an offensive shootout last week against the Baltimore Ravens 42-38. Down 35-14 entering the 4th quarter, the Dolphins outscored the Ravens 28-3 to claim the Week 2 victory. QB Tua Tagovailoa had a slow start, throwing 2 INTs, but he ended the game with 469 yards and 6 TDs. His top 2 receivers, WR Tyreek Hill and WR Jaylen Waddle, each showed their abilities with Hill having 11 receptions for 190 yards and 2 TDs while Waddle had 11 catches for 171 yards and 2 TDs. TE Mike Gesicki (4, 41, 1) also had a nice day to open up the offense.

The Dolphins defense will be a focal point this week against the Bills. Although they locked in late, only giving up 3 points in the final quarter, they struggled to contain duel-threat QB Lamar Jackson. Playing another duel-threat QB in Allen, they will just to adjust on the fly and contain him. Tua and company will have to have another big game in what is expected to be yet another offensive shootout.

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Bills at Dolphins odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:47 a.m. ET.

  • Money line (ML): Bills -210 (bet $210 to win $100) | Dolphins +175 (bet $100 to win $175)
  • Against the spread (ATS): Bills -4.5 (-110) | Dolphins +4.5 (-110)
  • Over/Under (O/U): 53.5 (O: -105 | U: -115)

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Bills at Dolphins key injuries

Bills

  • Micah Hyde (neck) out
  • CB Dane Jackson (neck) out
  • DT Ed Oliver (ankle) out
  • DT Jordan Phillips (ankle) out
  • MLB Matt Milano (neck) unspecified
  • FS Jordan Poyer (foot) questionable
  • WR Gabe Davis (ankle) questionable

Dolphins

  • CB Xavien Howard (groin) questionable
  • DT Raekwon Davis (knee) questionable

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Bills at Dolphins picks and predictions

Prediction

Bills 38, Dolphins 35

Money line

Lean BILLS (-210). Allen and the offense will make up for their defensive injuries. So far this season, the Bills have been able to consistently convert when they get to the red zone and that will need to continue in order to beat the Dolphins.

Against the spread

DOLPHINS +4.5 (-110) is the play. The Dolphins are on an ATS hot streak at home and in September. They are 6-1 ATS in their last 7 games in September and 6-1 ATS in their last 7 home games. With so many critical injuries to the Buffalo defense, Miami has the offensive fire power to stay close in this game. Hill and Waddle will open up the offense with their top-level speed while Tagovailoa and RBs Raheem Mostert and Chase Edmonds will keep the defense on their toes on the ground.

Over/Under

Take the OVER 53.5 (-105). Both these teams have many offensive weapons and coaches who know who to get them open. For the Bills, Allen is great at moving the ball around the offense and getting it to any player who is open. For the Dolphins, Tagovailoa is working with the speed of Hill and Waddle who can win their matchups more times than not.

The Over is 4-0 in the Bills last 4 games following a straight up win of more than 14 points, coach Josh McDaniel and Allen have a chemistry together that understand how to put the ball in the end zone. Furthermore, the Over is 10-4 in the last 14 meetings between these 2 teams.

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