Buffalo Bills at LA Rams odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at LA Rams odds and lines, with expert NFL picks and predictions.

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The Buffalo Bills (10-2) are visiting the LA Rams (6-6) Sunday for a marquee matchup in Week 14. Kickoff from SoFi Stadium is set for 4:25 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bills vs. Rams odds, and make our expert NFL picks and predictions.

The Bills have won 7 straight games, scoring at least 30 points in each of their last 6 games. At 10-2, they’re just 1 game behind the Kansas City Chiefs for the No. 1 seed in the AFC, and they hold the tiebreaker after winning their head-to-head matchup this season. Most recently, they crushed the San Francisco 49ers, 35-10, on Sunday Night Football in Week 13.

The Rams come into this one with a 6-6 record after winning just 2 of their last 4 games. They came back to beat the New Orleans Saints, 21-14, in Week 13, getting back to the .500 mark for the second time this season. They’ve yet to have a winning record at any point this year but they’ll have a chance to change that with a win over the Bills.

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Bills at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Friday at 8 p.m. ET.

  • Moneyline (ML): Bills -190 (bet $190 to win $100) | Rams +155 (bet $100 to win $155)
  • Against the spread (ATS): Bills -3.5 (-115) | Rams +3.5 (-105)
  • Over/Under (O/U): 49.5 (O: -110 | U: -110)

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Bills at Rams key injuries

Bills

  • WR Keon Coleman (wrist) questionable
  • TE Dalton Kincaid (knee) questionable

Rams

  • OL Alaric Jackson (foot) probable
  • OLB Jared Verse (ankle) probable

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Bills at Rams picks and predictions

Prediction

Bills 30, Rams 27

Moneyline

PASS on the moneyline. The Bills are on the road against a motivated Rams team, so they could be ripe for a letdown, especially after winning 7 games in a row. They’re just not worth betting on their own at -190.

Against the spread

The Bills have covered the spread in 3 straight games and 6 of their last 7, but the Rams are 4-2 ATS in their last 6 and have shown signs of improvement now that they’re fully healthy. The offensive line is at full strength, their receiving corps is healthy and the defense should be able to generate interior pressure against the Bills’ guards.

With the spread sitting at a key number of 3.5, BET RAMS +3.5 (-105) to cover and keep this one close.

Over/Under

The Bills have scored at least 30 points in 6 straight games and that’s not likely to change against a Rams defense that’s given up 582 rushing yards in their last 3 games, an average of 194 per game. The Rams, meanwhile, scored 21 points in the second half of Sunday’s win over the Saints and could find success running it against Buffalo’s defense, which is allowing 4.9 yards per carry.

BET OVER 49.5 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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