Boston Red Sox at Chicago White Sox odds, picks and predictions

Analyzing Friday’s Boston Red Sox at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

The Boston Red Sox (39-37) and Chicago White Sox (32-44) meet Friday for the opener of a 3-game series. First pitch from Guaranteed Rate Field is set for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Red Sox vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2023; Chicago won 4-2 last season

Boston lost 6-0 Thursday as a +122 road underdog vs. the Minnesota Twins. The Red Sox dropped back-to-back games on Wednesday and Thursday to split the 4 game series. Boston won 6 straight games from June 14-20, including the first 2 road games at Minnesota, and now sits at 18-19 on the road this season.

The White Sox lost 6-3 as -108 home favorites Wednesday vs. the Texas Rangers, losing the series 2-1. Chicago is 3-7 in its last 10 contests and has lost 4 of its last 5 games to fall to 18-19 at home on the season.

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Red Sox at White Sox projected starters

RHP Brayan Bello vs. RHP Lucas Giolito

Bello (4-4, 3.49 ERA) makes his 12th start. He has a 1.30 WHIP, 3.0 BB/9 and 8.6 K/9 through 59 1/3 IP.

  • Last outing: Win, 7 IP, 1 ER, 4 H, 3 BB, 8 K in a 6-2 home win Sunday vs. New York Yankees
  • First career start vs. Chicago

Giolito (5-4, 3.54 ERA) makes his 16th start. He has a 1.24 WHIP, 2.9 BB/9 and 9.3 K/9 through 86 1/3 IP.

  • Last outing: No-decision, 5 IP, 2 ER, 8 H, 3 BB, 5 K in a 4-3 road win Saturday vs. Seattle Mariners
  • Career vs. Boston: 1-1, 5.63 ERA (24 IP, 15 ER), 28 H, 14 BB, 29 K across 5 starts

Red Sox at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:40 a.m. ET.

  • Moneyline (ML): Red Sox -115 (bet $115 to win $100) | White Sox -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Red Sox -1.5 (+145) | White Sox +1.5 (-175)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Red Sox at White Sox picks and predictions

Prediction

White Sox 4, Red Sox 2

Moneyline

LEAN WHITE SOX (-105).

The Red Sox are the hotter team as they enter off wins in 6 of their last 8 games, but Chicago has got the better of Boston in recent meetings. The White Sox won 4 of 6 matchups in 2022, and the Red Sox are 1-5 in Bello’s last 6 series-opening starts, according to covers.com.

Run line/Against the spread

PASS.

The White Sox at +1.5 (-175) should be a pretty safe bet, but the line here is not worth the juice. Bet on the moneyline and/or O/U instead.

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Over/Under

LEAN UNDER 8.5 (-115).

The Under is 3-2-1 in Chicago’s last 6 outings and 5-2 in the past 7 Boston-Chicago meetings. The Under is also 6-0 in Chicago’s last 6 series openers and 4-0 in Giolito’s last 4 starts vs. the AL East, all per covers.com.

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