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The Boston Red Sox (28-27) and Baltimore Orioles (34-19) wrap up a 3-game series Wednesday. First pitch from Oriole Park at Camden Yards is scheduled for 6:35 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Red Sox vs. Orioles odds and make our expert MLB picks and predictions for the best bets.
Season series: Orioles lead 4-1
Boston was finally victorious over Baltimore in 2024, cashing as a (+158) road underdog in an 8-3 win Tuesday. Red Sox 3B Rafael Devers went 4 for 5 with a triple and 2 RBIs and is now tied with Jim Rice for the most extra-base hits before turning 28 in franchise history.
Despite a season-high 10 K’s, RHP Grayson Rodriguez took the loss as the 24-year-old was credited with 4 earned runs on 7 hits. Baltimore scored all 3 of its runs in the 1st inning as OF Colton Cowser drove in SS Gunnar Henderson, followed by a 2-run single from 3B Jordan Westburg.
Red Sox at Orioles projected starters
RHP Kutter Crawford vs. RHP Corbin Burnes
Crawford (2-3, 2.89 ERA) makes his 12th start. He has a 1.20 WHIP, 2.9 BB/9 and 8.8 K/9 in 62 1/3 IP.
- Last start: Loss, 4 1/3 IP, 6 ER, 7 H, 2 BB, 4 K in 7-2 home setback vs. Milwaukee Brewers Friday
- 2024 vs. Orioles: 0-0, 0.00 ERA (5 IP), 2 H, 4 BB, 6 K in 1 start, a 7-5 home loss April 10
Burnes (4-2, 2.60 ERA) makes his 12th start. He has a 1.07 WHIP, 2.3 BB/9 and 9.1 K/9 in 65 2/3 IP.
- Last start: No-decision, 6 IP, 3 ER, 7 H, 2 BB, 6 K in 6-4 win at Chicago White Sox Friday
- 2024 vs. Red Sox: 1-0, 1.29 ERA (7 IP, 1 ER), 2 H, 2 BB, 6 K in 1 start, a 7-1 road victory April 9
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Red Sox at Orioles odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:50 a.m. ET.
- Moneyline (ML): Red Sox +160 (bet $100 to win $160) | Orioles -190 (bet $190 to win $100)
- Run line (RL)/Against the spread (ATS): Red Sox +1.5 (-134) | Orioles -1.5 (+112)
- Over/Under (O/U): 7.5 (O: -106 | U: -114)
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Red Sox at Orioles picks and predictions
Prediction
Baltimore 6, Boston 4
Moneyline
INCLUDE ORIOLES (-190) IN A MONEYLINE PARLAY.
If you are an Orioles fan, this suggestion may sting, as Baltimore needs the New York Yankees to lose if it wants to climb back into 1st place in the AL East. However, the Yankees are in an advantageous spot against the last-place Los Angeles Angels, and their starter RHP Luis Gil has allowed only 2 ER in his last 30+ IP in May. Pairing the Yankees (-205 at Angels, 9:38 p.m. ET) with the Orioles (-190) pays out +127.
Run line/Against the spread
BET ORIOLES -1.5 (+112).
Entering this season, Burnes threw his cutter more than any other starter. Nonetheless, the 2nd-favorite to win the AL Cy Young (+450 at FanDuel Sportsbook) — behind only Detroit LHP Tarik Skubal (+270) — was able to induce 16 of 19 whiffs in his last start on non-cutters.
Meanwhile, Crawford’s 6 runs surrendered in his last start was a season high, and no team hits righties harder (34.1 hard hit %) than Baltimore. Tough to envision a scenario where the 28-year-old gets back on track in his 2nd start this year against this talented O’s lineup.
Over/Under
PASS.
The score prediction would indicate a heavy lean to the Over; however, with Burnes on the mound, I’ll pass.
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