Tight end
| 2017 | 2020 |
| Charles Clay | Dawson Knox |
| Logan Thomas | Tyler Kroft |
| Nick O’Leary | Tommy Sweeney |
| Keith Towbridge | Lee Smith |
| Jason Croom | Nate Becker |
| Wes Saxton | Jason Croom |
Advantage: 2020
This is a battle of two below-average tight end squads, but at best, the current unit is an average one. The Bills have never sported a modern-day tight end threat. But there’s hope Dawson Knox has potential to turn into one. He’s still young and hasn’t gotten there yet. Behind Knox, Tyler Kroft is by far a bigger threat than Logas Thomas or Nick O’Leary ever were, but the problem is keeping Kroft on the field.