Baltimore Orioles at St. Louis Cardinals odds, picks and predictions

Analyzing Monday’s Baltimore Orioles at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

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The Baltimore Orioles (29-15) and St. Louis Cardinals (20-26) open a 3-game series Monday night. First pitch at Busch Stadium is scheduled for 7:45 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Orioles vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Cardinals won 2-1 last season

RHP Corbin Burnes recorded a 5th consecutive quality start and finally got some run support as Baltimore defeated Seattle 6-3 Sunday, cashing as a (-141) home favorite. Burnes, who has the 2nd-shortest odds (+350 at FanDuel Sportsbook) to win the AL Cy Young behind Tigers LHP Tarik Skubal, tied a season high with 11 K’s.

The Cardinals failed to cash as a (+116) home underdog Sunday, falling 11-3 to the Red Sox. St. Louis had won 5 of their previous 6 games prior, and LF Brendan Donovan is currently riding a 7-game hit streak.

Orioles at Nationals projected starters

RHP Dean Kremer vs. RHP Sonny Gray

Kremer (3-3, 3.72 ERA) makes his 9th start. He has a 1.02 WHIP, 2.9 BB/9 and 9.2 K/9 in 46 innings.

  • Last start: Loss, 3 ER, 4 H, 4 BB, 10 K in 9-2 defeat vs. Arizona May 12
  • His 1.8 HR/9 is 2nd-highest in AL among qualified pitchers behind only White Sox RHP Michael Soroka (1.9)

Gray (5-2, 3.05 ERA) makes his 8th start. He has a 1.06 WHIP, 1.7 BB/9 and 11.5 K/9 in 41 1/3 innings.

  • Last start: Win, 6 IP, 5 ER, 8 H, 2 BB, 9 K in 7-6 victory at Angels May 14
  • His K/9 is 5th-best among 108 pitchers with at least 40 IP this season

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Orioles at Cardinals odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:35 a.m. ET.

  • Moneyline (ML): Orioles +104 (bet $100 to win $104) | Cardinals -122 (bet $122 to win $100)
  • Run line (RL)/Against the Spread (ATS): Orioles -1.5 (+164) | Cardinals +1.5 (-215)
  • Over/Under (O/U): 8 (O: -104 | U: -118)

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Orioles at Cardinals picks and predictions

Prediction

Orioles 5, Cardinals 3

Moneyline

BET ORIOLES FIRST 5 INNINGS (+114).

Why not take the extra profit? Plus, you can get your money back if it’s a tie after 5 innings. Gray was unable to defeat Baltimore in either of his outings against it last season as a member of the Twins, and Orioles SS Gunnar Henderson leads MLB (along with Astros RF Kyle Tucker) in home runs this season.

Run line/Against the spread

BACK BALTIMORE -1.5 (+164).

Henderson homered in 3 straight games against the Mariners over the weekend, and the 22-year-old enters Monday with the 4th-shortest odds to win AL MVP (+550 at FanDuel Sportsbook). As a team, the Orioles lead the league in HRs along with the Yankees (68), while only the Brewers and Marlins bullpens have served up more dongs than the Cardinals pen (20).

St. Louis may be able to hang tight in the early innings as the O’s get their footing on this 7-game road trip, but Baltimore is a World Series contender and should pull away late. In this instance, taking a shot on laying a run and a half is worth it.

Over/Under

PASS.

Tough to recommend an Under with Kremer pitching, especially since he allowed 5 runs in 4 1/3 innings last season vs. the Cardinals. However, Baltimore’s offense put up 11 runs in a winning effort in that September game, and it is still certainly capable of supporting its pitcher if he stumbles once again.

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