Arizona Diamondbacks at San Francisco Giants odds, picks and prediction

Analyzing Thursday’s Arizona Diamondbacks at San Francisco Giants odds and lines, with MLB picks and predictions.

The Arizona Diamondbacks (50-108) close out their final road series of the season with the third and final game of their series against the San Francico Giants (104-54), while hoping to salvage one game of the series. First pitch is at 9:45 p.m. at Oracle Park. Let’s analyze the lines around the Diamondbacks vs. Giants odds with MLB picks and predictions.

Diamondbacks LHP Madison Bumgarner (7-10, 4.58 ERA) makes his 26th start. He has a 1.17 WHIP, 2.5 BB/9 and 7.6 K/9 through 141 1/3 IP.

  • Lost each of his last three decisions and has not picked up a win since Aug. 19.
  • Has made two starts against his former teams since joining the Diamondbacks in 2020. He is 1-1 with 3 ER over 11 IP. In his last start against them Aug. 3, he allowed only 1 run on 6 hits over 7 innings and picked up the win in a 3-1 Arizona victory.

Giants LHP Scott Kazmir (0-1) makes his fourth start and fifth appearance of the season. He has allowed 5 ER on 12 H and 4 BB with 10 K through 11 IP.

  • Has not pitched more than 4 innings in any start this season. Gave up 1 unearned run on 4 hits and 3 walks over 4 innings against the San Diego Padres Sept. 22.
  • Has not allowed more than 2 runs in any appearance this season.

Diamondbacks at Giants odds, lines, picks and prediction

MLB odds courtesy of Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 3:43 p.m. ET.

  • Money line: Diamondbacks +175 (bet $100 to win $175) | Giants -220 (bet $220 to win $100)
  • Against the spread/ATS: Diamondbacks +1.5 (-117) | Giants -1.5 (-103)
  • Over/Under: 8.5 (O: -108 | U: -112)

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Prediction

Giants 6, Diamondbacks 3

Money line (ML)

The Giants have absolutely owned the Diamondbacks this season and have won 16 of the 18 games in the head-to-head season series.

Arizona has only three wins over its last 15 games and has the worst record in the majors. The D-Backs’ 20-60 road record is the worst in the majors.

Take the GIANTS (-220).

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Run line/Against the spread (ATS)

The Diamondbacks have fared better against the spread in their games against the Giants, and they’re 8-10 ATS against them. However, they are 37-43 ATS on the road for the fifth-worst mark in baseball.

The Giants are 42-35 ATS at home and 7-3 ATS across their last 10 games.

Take the GIANTS -1.5 (-103).

Over/Under (O/U)

Eleven of the 18 games between the two teams this season finished with a total of 9 or more runs.

Seven of the Diamondbacks’ last 11 games had a total of 9 or more runs. Six of the last eight games for the Giants finished with 9 or more runs.

Take OVER 8.5 (-108).

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