Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

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The Arizona Diamondbacks (39-51) face the San Diego Padres (51-41) Saturday for the middle game of a 3-game set in San Diego. First pitch is set for 8:40 p.m. ET at Petco Park. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 8-2

The Diamondbacks lost Friday’s opener 5-3 and have dropped 3 straight. They are 2-7 in their last 9 games.

The Padres, who snapped a 3-game losing streak with the win, are 6-13 in their last 19 games.

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Diamondbacks at Padres projected starters

LHP Tyler Gilbert vs. LHP Sean Manaea

Gilbert (0-3, 5.33 ERA) makes his 6th start in 7 appearances. He has a 1.26 WHIP, 2.8 BB/9 and 6.0 K/9 through 25 1/3 IP.

  • D-backs are 1-4 in his 5 starts this season
  • Coming off his best start of the season, pitching 5 2/3 scoreless innings in a no-decision against the visiting Colorado Rockies Sunday
  • Career vs. Padres: 1-1, 1.69 ERA (16 IP, 3 ER), 9 H, 5 BB, 11 K in 2 starts and 1 relief appearance, all in 2021

Manaea (4-4, 4.09 ERA) makes his 17th start. He has a 1.21 WHIP, 3.4 BB/9 and 9.2 K/9 through 94 2/3 IP.

  • 2022 vs. Diamondbacks: 1-0, 2.37 ERA (19 IP, 5 ER), 7 H, 7 BB, 20 K in 3 starts – Padres went 2-1
  • 2022 home splits: 2-3, 4.54 ERA (39 2/3 IP, 20 ER), 1.44 WHIP, 8.2 K/9 in 7 starts

Diamondbacks at Padres odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:25 p.m. ET.

  • Money line (ML): Diamondbacks +160 (bet $100 to win $160) | Padres -200 (bet $200 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-135) | Padres -1.5 (+110)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 5, Diamondbacks 4

Money line

Arizona has struggled against San Diego this season, losing 8 out of 10. The D-backs have also lost 5 of their last 7 road games.

Manaea has pitched well against Arizona, while Gilbert has been inconsistent.

But at -200, this is a PASS. There are better bets to be made.

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Run line/Against the spread

The Diamondbacks are 50-40 ATS on the season, including 24-18 ATS on the road.

San Diego is only 15-29 ATS at home and 44-48 ATS overall.

While the D-backs have lost 7 of their last 9 games, they lost by 1 run in 4 of those losses.

Take the DIAMONDBACKS +1.5 (-135).

Over/Under

Six of this season’s 10 games between the teams this season have had 7 or fewer runs.

But 10 of the last 14 games for Arizona have had 8 or more runs.

The Padres’ last 6 games have all had 8 or more runs.

Take OVER 7.5 (-130).

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