Arizona Diamondbacks at Baltimore Orioles odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at Baltimore Orioles odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (18-21) and Baltimore Orioles (25-12) meet Saturday as the defending NL Champions look to get back on track after seeing their 4-game winning streak snapped Friday. First pitch from Oriole Park at Camden Yards is scheduled for 4:05 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Orioles odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 1-0.

Baltimore defeated Arizona Friday 4-2, cashing as a (-128) home favorite. SP Cole Irvin earned his 4th win in as many starts as the 30-year-old struck out 6 in 5.2 IP. DH Ryan O’Hearn walked and drove in SS Gunnar Henderson with an RBI single in the 5th inning.

Diamondbacks at Orioles projected starters

RHP Ryne Nelson vs. LHP John Means

Nelson (2-2, 5.23 ERA) makes his 6th start. He has a 1.60 WHIP, 2.61 BB/9 and 6.97 K/9 in 20.2 innings.

  • Last start: Win, 5 IP, 4 ER, 8 H, 1 BB, 3 K in 11-4 win over San Diego Sunday
  • Has a 7-4 record with a 3.25 ERA in 102.1 IP on the road compared to a 4-7 record, 7.03 ERA in 80.1 IP at Chase Field.

Means (1-0, 0.00 ERA) makes his 2nd start for the Orioles after making 6 down at AAA while recovering from injury. In 6 games for Norfolk, Means had an 8.68 ERA, although he did go 7 scoreless in his final rehab outing.

  • Last start: Win, 7 IP, 0 ER, 3 H, 0 BB, 8 K in 2-1 win over Cincinnati last Saturday
  • Induced more swing and misses in his 1st start back than when he pitched a no-hitter back in 2021 vs Seattle.

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Diamondbacks at Orioles odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:45 a.m. ET.

  • Moneyline (ML): Diamondbacks +142 (bet $100 to win $142) | Orioles -168 (bet $168 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-140) | Orioles -1.5 (+116)
  • Over/Under (O/U): 8.5 (O: -122 | U: +100)

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Diamondbacks at Orioles picks and predictions

Prediction

Baltimore 5, Arizona 2

Moneyline

PASS.

When the expectation is that Orioles will win by multiple runs, laying that much juice on the MoneyLine is not necessary,

Run line/Against the spread

BET ORIOLES -1.5 (+116).

Baltimore should be able to score multiple runs thanks to Henderson, who is tied with 1B Bryce Harper for 2nd highest hard-hit percentage (50.0%) vs. RHP among 192 qualified hitters. 3B Jordan Westburg, who has doubles in consecutive games and sports the 14th-best hard hit % vs. RHP (41.7%) should also help contribute for a deep Orioles lineup.

Over/Under

BET UNDER 8.5 (+100).

Even if it includes a minor league game, Means has been outstanding in his last 2 starts, and his opponent is no juggernaut offensively. Diamondbacks OF Corbin Carroll, last year’s NL Rookie of the Year is batting .200 this season and is 1 for his last 12. Slugger 1B Christian Walker has yet to homer this month, and it seems unlikely he will Saturday since Baltimore is not the HR haven it once was.

RP Yennier Cano entered into Friday’s game and picked up his 2nd save, so perhaps Baltimore can be stable once again in their back end. For Arizona, as long as Nelson can press the zone with his fastball like he did in a successful start this year vs. St. Louis, Baltimore’s big bats could stay in check at least initially enough for this game to stay Under.

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