The Arizona Cardinals (6-4) visit the New England Patriots (4-6) Sunday of Week 12 for a 1 p.m. ET kickoff. Below, we preview the Cardinals-Patriots betting odds and lines and make our NFL picks and predictions.
Cardinals at Patriots: Betting odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 5:25 p.m. ET.
- Money line: Cardinals -125 (bet $125 to win $100) | Patriots +105 (bet $100 to win $105)
- Against the spread/ATS: Cardinals -1.5 (-110) | Patriots +1.5 (-110)
- Over/Under: 49.5 (O: -110 | U: -110)
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Cardinals at Patriots: Game notes
- New England is winless against the NFC this season.
- The Cardinals are No. 2 in the league in total offense and rushing yards per game and No. 8 in scoring.
- The Patriots are only 27th in scoring.
- Cardinals QB Kyler Murray has passed for 2,644 yards with 19 touchdowns and eight interceptions, while rushing for 619 yards and 10 touchdowns, leading the league with a 6.7-yard per-rush average.
- Patriots QB Cam Newton has only four touchdown passes to seven interceptions this season, but he has nine rushing touchdowns.
Cardinals at Patriots: Key injuries
Cardinals
- TE Darrell Daniels (ankle) out
- WR Larry Fitzgerald (COVID-19) out
- DE Josh Mauro (hamstring) out
- OL Justin Murray (hand) questionable
- QB Kyler Murray (shoulder) probable
- WR Trent Sherfield (COVID-19 list) out
- S Jalen Thompson (ankle) out
Patriots
- LB Ja’Whaun Bentley (groin) questionable
- DL Adam Butler (shoulder) questionable
- RB Rex Burkhead (knee) out
- S Kyle Dugger (toe) questionable
- PK Nick Folk (back) questionable
- CB Stephon Gilmore (knee) questionable
- DL Lawrence Guy (shoulder, elbow, knee) questionable
- WR N’Keal Harry (shoulder) questionable
- TE Ryan Izzo (hamstring, hand) questionable
- G Shaq Mason (calf) questionable
- OL Joe Thuney (ankle) questionable
- OL Isaiah Wynn (knee) doubtful
Cardinals at Patriots: Odds, betting lines, predictions and picks
Prediction
Cardinals 30, Patriots 23
Money line (?)
The Cardinals have no problem moving the football and scoring points offensively. There is no individual matchup where the Patriots really have an advantage. New England will be able to have some success running the ball, but if Arizona builds a lead, the Pats will have to rely on the passing game. The Cardinals, coming off a disappointing loss against the Seahawks, are extra rested. Take the CARDINALS -125.
Against the spread (?)
Arizona is 5-5 ATS this season and New England is 4-6 ATS. But a 1.5-point spread is too small to go with the Pats if you think the Cardinals will win outright. You can’t reasonably predict a one-point win. Take the CARDINALS -1.5 (-110).
Over/Under (?)
The total is low for a Cardinals game, even though they are 3-7 O/U this season. The total in their games has gone Over in three of their last four contests. The Cardinals have been consistently hitting 30 points and I expect nothing less. Take OVER 49.5 (-110).
Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.
Also see:
- WRs Fitzgerald, Sherfield placed on reserve/COVID-19 list (Cards Wire)
- RB Michel should be ‘ready to go’ in Week 12 (Patriots Wire)
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