The Arizona Cardinals (8-7) meet the Los Angeles Rams (9-6) Sunday in Week 17 both with the playoffs in an NFC West showdown. Kickoff is at 4:25 p.m. ET at SoFi Stadium in Inglewood, CA.
Below, we preview the Cardinals-Rams betting odds and lines and make our NFL picks and predictions.
Cardinals at Rams: Betting odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 9:30 a.m. ET.
- Money line: Cardinals -185 (bet $185 to win $100) | Rams +155 (bet $100 to win $155)
- Against the spread/ATS: Cardinals -3 (-120) | Rams +3 (+100)
- Over/Under: 40.5 (O: -110 | U: -110)
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Cardinals at Rams: Game notes
- The Cardinals must win to make the playoffs. The Rams will make the postseason with either a win or if the Chicago Bears lose in Week 17.
- Rams QB John Wolford will be making his NFL debut.
- Cardinals OLB Haason Reddick has 7.5 sacks and six forced fumbles in his last three games.
- Arizona allowed 227 rushing yards in Week 16 in a 20-12 loss to the San Francisco 49ers.
- The Rams have beaten the Cardinals seven straight games. They have not lost to Arizona since Sean McVay became head coach.
Cardinals at Rams: Key injuries
Cardinals
- RB Chase Edmonds (hip) questionable
- WR Larry Fitzgerald (groin) questionable
- S Budda Baker (neck) questionable
Rams
- QB Jared Goff (thumb) out
- RB Cam Akers (ankle) questionable
- OLB Leonard Floyd (abdomen) questionable
- WR Cooper Kupp (COVID-19 list) out
- DT Michael Brockers (COVID-19 list) out
Cardinals at Rams: Odds, betting lines, predictions and picks
Prediction
Cardinals 23, Rams 16
Money line (?)
The Cardinals have struggled over the last six weeks but the Rams have also struggled offensively in their two-game losing streak and now will be missing their starting quarterback, leading rusher and leading receiver. While the Rams do have the No. 1 defense, the Cardinals put up 28 points against them in Week 13 despite only gaining 232 total yards. The Rams just won’t be able to put up enough points. Take the CARDINALS (-185).
Against the spread (?)
Arizona is 7-8 ATS and the Rams are 8-7 ATS. They have covered the spread in each of their last two wins. The Rams, who have only been underdogs four other times this season, are 2-2 ATS as underdogs. Take the CARDINALS -3 (-120).
Over/Under (?)
The total began the week at 38.5 but moved to 40.5 once it was known that Cardinals QB Kyler Murray would play. The two teams went Over in their Week 13 matchup but the combination of the Rams’ No. 1 defense and the sheer lack of talent playing on offense for L.A. means a low-scoring affair. Take UNDER 40.5 POINTS (-110).
Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.
Also see:
- Rams offense presents almost identical challenges Cardinals faced in Week 16 (Cards Wire)
- Sean McVay’s New Year’s Eve consisted of red-zone planning for Week 17 (Rams Wire)
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