Alabama vs. Mississippi State: Prediction, point spread, odds best bet

Alabama opens as 21.5-point favorite over Mississippi State

The Alabama Crimson Tide plays the Mississippi State Bulldogs on Oct. 22, and if you’re looking to do some betting research, you’re in luck. We’ll give you the latest point spread, money line odds and over/under number, as well as the information you’ll need to make the smartest bet at Bet MGM Sportsbook.

The game starts at 6:00 p.m. CDT and can be seen on ESPN.

The Crimson Tide are coming off their first loss of the year and first loss to Tennessee in 15 years. The Tide committed 17 penalties and played one of the sloppiest games of the Saban era, and they paid the price for it.

While the loss to Tennessee hurts, Alabama can not skip over Mississippi State which has spent parts of the year ranked.  They have one of the best passing attacks in the country, but they will get an angry Alabama team that’s seeing red.