Buffalo Bills at Detroit Lions odds, picks and predictions

[gambcom-standard rankid=”4141″ ]

The Buffalo Bills (10-3) take on the Detroit Lions (12-1) Sunday in Week 15. Kickoff from Ford Field is set for 4:25 p.m. ET (CBS). Below, we look at Bills vs. Lions odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Bills were marched out of town by the LA Rams in a 44-42 defeat in Week 14. They made a late push, down 38-21 in the fourth quarter, but it wasn’t enough. QB Josh Allen had a huge game, going 22-for-37 for 342 yards, 3 TDs and 0 INTs while rushing 10 times for 82 yards and 3 more TDs.

The Lions won their 11th straight in a 34-31 win over the Green Bay Packers Dec. 5. QB Jared Goff was 32-for-41 for 283 yards, 3 TDs and 1 INT. He spread the ball around to 6 different receivers that had 5 grabs apiece. WR Tim Patrick introduced himself with a 6-43-2 evening.

Play our free daily Pick’em Challenge and win! Play now!

Bills at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 5:42 p.m. ET.

Moneyline (ML): Bills +120 (bet $100 to win $120) | Lions -145 (bet $145 to win $100)
Against the spread (ATS): Bills +2.5 (-110) | Lions -2.5 (-110)
Over/Under (O/U): 54.5 (O: -110 | U: -110)

WIN YOUR FANTASY FOOTBALL LEAGUE!
The Huddle has been turning players like you into winners for over 25 years. This season, it’s your turn. Custom fantasy football rankings, sleepers and tools are just a click away. Save 25% off the Internet’s best-kept secret. Subscribe now!

[gambcom-standard rankid=”4132″ ]

Bills at Lions key injuries

Bills

CB Rasul Douglas (knee) out
S Damar Hamlin (back, ribs) questionable
TE Dalton Kincaid (knee) questionable
S Taylor Rapp (neck, shoulder) questionable

Lions

LB Trevor Nowaske (concussion) out

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Bills at Lions picks and predictions

Prediction

Bills 24, Lions 20

Moneyline

I’m taking Buffalo here. They’re getting Kincaid back, despite his questionable tag, and WR Keon Coleman (wrist) returns as well. Allen is playing on another level right now as he seeks his first MVP award. The Lions have been off for 10 days and don’t really need to be as hungry at 12-1.

Take the BILLS +120.

Against the spread

I’d consider the Bills’ side of the spread if it swells to 3.5 by kickoff. There’s no point in taking it here, though. Instead, give me JOSH ALLEN ANYTIME TOUCHDOWN (+115). He has one in 4 straight games and 6 during that span.

Over/Under

I like the Under here in a defensive struggle. The Lions are 2-3-1 O/U in their last 6. Buffalo is 4-0-1 in its last 5, but that’s thanks to scoring 30+ points in 7 straight games. That’s not happening here.

Take the UNDER 54.5 (-110).

[gambcom-standard rankid=”6305″ ]

Want to play some games of your own? Play for free at the best social casinos and enjoy lots of slots, blackjack, video poker, roulette and more. You can even earn real prizes!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Ryan Dodson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]