Seattle Seahawks at San Francisco 49ers odds, picks and predictions

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The Seattle Seahawks (4-5) are on the road in Week 11 taking on the San Francisco 49ers (5-4). Kickoff from Levi’s Stadium is Sunday at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Seahawks vs. 49ers odds, and make our expert NFL picks and predictions.

The Seahawks, coming off their bye, have lost 2 straight games and 5 of their last 6 after a 3-0 start to the season. Their last game was a 26-20 overtime home loss to the LA Rams as 1-point underdogs.

The 49ers have won 2 in a row. They beat the Tampa Bay Buccaneers 23-20 on the road last week on a last-second field goal by K Jake Moody. They failed to cover the 6.5-point spread as favorites.

The 49ers won the first meeting this year 36-24 in Seattle in Week 6.

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Seahawks at 49ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 12:21 a.m. ET.

Moneyline (ML): Seahawks +240 (bet $100 to win $240) | 49ers -300 (bet $300 to win $100)
Against the spread (ATS): Seahawks +6.5 (-110) | 49ers -6.5 (-110)
Over/Under (O/U): 48 (O: -110 | U: -110)

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Seahawks at 49ers key injuries

Seahawks

TE Noah Fant (groin) out
TE Brady Russell (foot) out
C Connor Williams (personal – announced retirement) out

49ers

OL Aaron Banks (thigh) questionable
DE Nick Bosa (hip) questionable
DT Kevin Givens (groin) out
OL Jon Feliciano (knee) questionable
DE Yetur Gross-Matos (knee) questionable
CB Darrell Luter (pelvis) doubtful
TE George Kittle (hamstring) questionable
CB Charvarius Ward (personal) out
OL Trent Williams (ankle) questionable
P Mitch Wishnowsky (back) out

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Seahawks at 49ers picks and predictions

Prediction

49ers 27, Seahawks 23

Moneyline

Seattle has allowed 29.7 points per game in the 6 games after their 3-0 start while San Francisco has allowed between 20 and 28 points in each of their last 5 games.

The Niners have beaten the Seahawks in 6 straight games. San Fran can tie the idle Arizona Cardinals atop the NFC West with a win. They should pick up the win,, even though they are banged up, but -300 odds aren’t worth the action.

PASS.

Against the spread

The 49ers are 5-1 ATS in their last 6 games against Seattle, but their wins in the last 2 games have not been by more than 6 points.

Four of Seattle’s losses this season have been by more than 6 points, but with so many injuries for the Niners, this will stay close.

BET SEAHAWKS +6.5 (-110).

Over/Under

Their first meeting had 60 total points, but only 2 of the last 6 games for the Niners have surpassed 48. None of the last 3 games for the Seahawks have topped 48.

But with the Seahawks allowing nearly 30 points per game in the last 6 contests and San Francisco’s opponents averaging 24 over the last 5, expect some points.

BET OVER 48 (-110).

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