Denver Broncos at Seattle Seahawks odds, picks and predictions

Analyzing Sunday’s Denver Broncos at Seattle Seahawks odds and lines, with expert NFL picks and predictions.

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The Denver Broncos and Seattle Seahawks open their seasons Sunday. Kickoff from Lumen Field is scheduled for 4:05 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook’s lines around the Broncos vs. Seahawks odds, and make our expert NFL picks and predictions.

The Broncos will have rookie QB Bo Nix in the starting lineup to lead Denver’s offense. They cut QB Russell Wilson in the offseason. It is their second season under coach Sean Payton and defensive coordinator Vance Joseph

The Seahawks have familiar faces with QB Geno Smith still starting with the same offensive weapons as before, but they have a first-year coach in Mike Macdonald. They have beefed up their defensive line, re-signing Leonard Williams and drafting Byron Murphy II in the 1st round this year. No one knows what the Seahawks will be in their first year in over a decade without Pete Carroll leading the way.

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Broncos at Seahawks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 1:55 p.m. ET.

  • Moneyline (ML): Broncos +200 (bet $100 to win $200) | Seahawks -250 (bet $250 to win $100)
  • Against the spread (ATS): Broncos +6 (-110) | Seahawks -6 (-110)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

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Broncos at Seahawks key injuries

Broncos

  • None

Seahawks

  • TE Pharaoh Brown (foot) out
  • WR Tyler Lockett (thigh) questionable
  • LB Uchenna Nwosu (knee) out

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Broncos at Seahawks picks and predictions

Prediction

Seahawks 27, Broncos 24

Moneyline

The Broncos scored a lot of points in the preseason, which doesn’t mean it will transfer to the regular season, but at least there is some trend. They scored 33 points per game in the preseason.

RB Javonte Williams should find success in the running game against a defense that is going to take time to jell. Last year, even with Williams clogging up the defensive interior, Seattle (-250) allowed 175.1 rushing yards per game over their final 7 games.

With a rookie QB in Nix, there will be mistakes, so I can’t predict an outright Broncos win.

That said, -250 odds to bet on the favored Seahawks isn’t worth the action.

PASS.

Against the spread

We don’t know enough about either team to know what they will be. They both appear to be kind of the same. They were subpar teams last season and it looks like this could be a transition year — Denver because of a rookie QB and Seattle because of a first-year coach.

That’s why the 6-point spread seems crazy. Neither team, on paper, is significantly better than the other.

BET BRONCOS +6 (-110).

Over/Under

Denver had no problems scoring in the preseason. Seattle has a running game with RB Kenneth Walker III, and even potentially missing Lockett, Smith has weapons to throw it to in WRs DK Metcalf and Jaxon Smith-Njigba. 

Seattle scored 33 in its preseason finale but only had 31 combined points in its first 2 games.

BET OVER 41.5 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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