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The Baltimore Orioles (30-18) and Chicago White Sox (15-36) play the 2nd game of a 4-game series Friday. First pitch from Guaranteed Rate Field is scheduled for 7:40 p.m. ET (Apple TV+). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. White Sox odds and make our expert MLB picks and predictions for the best bets.
Season series: Orioles lead 1-0
The Orioles snapped a 3-game losing streak with an 8-6 win over the White Sox Thursday to cash as -224 road favorites. C Adley Rutschman and 2B Jorge Mateo led the way on offense with 3 RBIs each, while RHP Grayson Rodriguez allowed 2 ER in 5 innings and picked up the win.
The White Sox have lost back-to-back games after Thursday’s setback as +202 home underdogs. DH Gavin Sheets and LF Andrew Benintendi each had 2 RBIs, and RHP Mike Clevinger allowed 5 ER in 4 2/3 innings to pick up the loss.
Orioles at White Sox projected starters
RHP Corbin Burnes vs. RHP Chris Flexen
Burnes (4-2, 2.56 ERA) makes his 11th start. He has a 1.04 WHIP, 2.3 BB/9 and 9.1 K/9 in 59 2/3 innings.
- Orioles are 6-4 in his starts
- Has allowed 3 or fewer ER in each outing
- Has allowed 17 ER and 6 HR this season while striking out 60 and walking 15
Flexen (2-4, 5.48 ERA) makes his 9th start and 11th appearance. He has a 1.35 WHIP, 3.1 BB/9 and 6.4 K/9 in 44 1/3 innings.
- White Sox are 2-6 in his starts
- Has allowed 27 ER and 7 HR while striking out 34 and walking 15
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Orioles at White Sox odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:36 a.m. ET.
- Moneyline (ML): Orioles -275 (bet $275 to win $100) | White Sox +220 (bet $100 to win $220)
- Run line (RL)/Against the spread (ATS): Orioles -2.5 (+105) | White Sox +2.5 (-125)
- Over/Under (O/U): 8 (O: -115 | U: -105)
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Orioles at White Sox picks and predictions
Prediction
Orioles 6, White Sox 3
Moneyline
PASS.
There is no value on the Orioles (-275) to beat a White Sox team that is 3-7 in its last 10 games.
Run line/Against the spread
LEAN ORIOLES -2.5 (+105).
Two of the Orioles’ last 3 wins have come by 3 or more runs, and the team has scored 3 or more in 7 of its last 8 games. Five of Chicago’s last 7 losses have come by 3 or more runs, including 3 of its last 4. It has scored 2 or fewer runs in 6 of its last 10 games.
Over/Under
BET OVER 8 (-115).
The Orioles have hit the Over in 6 of their last 10 games and scored 4 or more runs in 3 of their last 5. They have hit the Over in 4 of their last 5 games. The White Sox have allowed 6 or more runs in 4 of their last 5 games, including 8 or more in each of their last 2.
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