Detroit Tigers at Arizona Diamondbacks odds, picks and predictions

Analyzing Friday’s Detroit Tigers at Arizona Diamondbacks odds and lines, with MLB expert picks, predictions and best bets.

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The Detroit Tigers (21-22) and Arizona Diamondbacks (21-23) open a 3-game set at Chase Field Friday. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Tigers vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Diamondbacks won 3-0 last season

The Tigers are coming off a 2-0 loss as -157 home favorites against the Miami Marlins Wednesday with the Under (9) easily cashing. Detroit lost 2 of 3 against Miami, the team with the worst record in MLB.

The Diamondbacks beat the Cincinnati Reds 2-1 in Phoenix Wednesday as the Under (8.5) hit. LF Lourdes Gurriel Jr. hit a go-ahead RBI double in the 8th inning for Arizona, which cashed as a -148 favorite.

Tigers at Diamondbacks projected starters

LHP Tarik Skubal vs. RHP Ryne Nelson

Skubal (5-0, 2.02 ERA) makes his 9th start. He has a 0.86 WHIP, 1.5 BB/9 and 11.0 K/9 in 49 IP.

  • Last start: Win, 6 1/3 IP, 2 ER, 7 H, 2 BB, 7 K in 8-2 home victory vs. Houston Astros Saturday
  • 2024 road stats: 2-0, 1.00 ERA (18 IP, 2 ER), 0.67 WHIP in 3 starts
  • Has never faced Diamondbacks

Nelson (2-2, 5.33 ERA) makes his 7th start. He has a 1.70 WHIP, 2.1 BB/9 and 6.8 K/9 in 25 1/3 IP.

  • Last start: No-decision, 4 2/3 IP, 3 ER, 10 H, 0 BB, 3 K in 5-4 loss in 11 innings at Baltimore Orioles Saturday
  • 2024 home stats: 2-1, 5.93 ERA (13 2/3 IP, 9 ER), 1.90 WHIP in 3 starts
  • Career vs. Tigers: 1-0, 0.00 ERA (5 2/3 IP), 4 H, 2 BB, 4 K in 1 start, a 5-0 road victory June 10, 2023

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Tigers at Diamondbacks odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:24 p.m. ET.

  • Moneyline (ML): Tigers -145 (bet $145 to win $100) | Diamondbacks +120 (bet $100 to win $120)
  • Run line (RL)/Against the spread (ATS): Tigers -1.5 (+125) | Diamondbacks +1.5 (-150)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Tigers at Diamondbacks picks and predictions

Prediction

Tigers 3, Diamondbacks 2

Moneyline

Detroit (-145) being a favorite at the defending NL champs, after losing back-to-back games to the team with the worst record in MLB, speaks volumes to how good of a spot this is for the Tigers. Skubal is obviously the superior starter, and Arizona struggled in its last 2 games against Cincinnati’s pitching staff.

However, since Skubal is the main reason to back the Tigers, playing them in the 1st 5 innings is the safer bet.

BET TIGERS FIRST 5 INNINGS (-145).

Run line/Against the spread

Detroit has not covered a RL as a favorite in 4 straight games, and Arizona +1.5 (-150) is too expensive for a team that is expected to score 3 or fewer runs.

PASS. Bet Detroit first 5 and/or the total instead.

Over/Under

Neither offense has been impressive lately. Detroit has been shut out in back-to-back games, and Arizona has scored a total of just 4 runs over its last 2 outings. Skubal has allowed 2 ER or fewer in 6 straight games and should continue to dominate against a struggling Arizona offense.

BET UNDER 8 (-110).

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