Giants vs. 49ers: Week 3 staff picks and predictions

The Giants Wire staff offer their picks and predictions ahead of a Week 3 game between the New York Giants and San Francisco 49ers.

The New York Giants (1-1) will take on the San Francisco 49ers (2-0) this Thursday night at Levi’s Stadium in their third game of the 2023 regular season.

Opening the week, the Giants were a 10-point road underdog, and that got a bit worse (+11) before returning to where it started. As of this writing, New York is +10.

How does the Giants Wire staff see this Week 3 battle shaking out? Here’s a look at our picks and score predictions: