Detroit defeated Kansas City, 21-20, Thursday at Arrowhead Stadium in Kansas City, Missouri.
Three former Vols appeared in the season-opening game.
Cameron Sutton started at cornerback for the Lions and did not record any statistics. Sutton played in his first game with Detroit after signing as a free agent from Pittsburgh.
Linebacker Jalen Reeves-Maybin recorded one tackle and rushed for three yards on one attempt during a fake punt.
Trey Smith started at guard for the Chiefs.
Defensive back Emmanuel Moseley was inactive for the Lions and rookie quarterback Hendon Hooker is on injured reserve for Detroit.