First look: Ohio State at Indiana odds and lines

Looking at Saturday’s Ohio State at Indiana college football odds, lines and trends. Here’s what you need to know.

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The Ohio State Buckeyes and the Indiana Hoosiers open the regular season on Saturday at Memorial Stadium in Bloomington, Ind. Kickoff is scheduled for 3:30 p.m. ET (CBS). Below, we look at Ohio State at Indiana odds from BetMGM Sportsbook. Also see: SportsbookWire’s college football picks and predictions.

The Buckeyes lost QB C.J. Stroud and WR Jaxon Smith-Njigba, among others, to the NFL. But in Columbus, they tend to reload and move on. QB Kyle McCord is expected to take the reins of the offense, with perhaps WR Devin Brown factoring in, too. Either signal caller will have one of the top targets in the country in WR Marvin Harrison Jr.

Defensively, the Buckeyes need improvement after a so-so season. LBs Steele Chambers and Tommy Eichenberg are the next great Ohio State linebackers, but there are some questions in the secondary. The D-line should be improved, though.

For Indiana, it has won just 6 total games across the past 2 seasons, and only 2 games inside the conference. The Hoosiers have 7 total starters back from a season ago, so IU went to the transfer portal rather feverishly. Facing a national title contender in the opener while trying to get a slew of new starters in place is a tall order.

Ohio State is No. 4 in the USA TODAY Sports AFCA Coaches Poll.

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Ohio State at Indiana odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 7:29 p.m. ET.

  • Moneyline (ML): Ohio State -10000 (bet $10,000 to win $100) | Indiana +1600 (bet $100 to win $1,600)
  • Against the spread (ATS): Ohio State -29.5 (-110) | Indiana +29.5 (-110)
  • Over/Under (O/U): 59.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Ohio State 11-2 | Indiana 4-8
  • ATS: Ohio State 6-6-1 | Indiana 4-8
  • O/U: Ohio State 10-3 | Indiana 7-5

Ohio State at Indiana head-to-head

These 2 Big Ten combatants last opened the season on Aug. 31, 2017, in Bloomington, with the Buckeyes rolling to a 49-21 victory as 20-point favorites while nearly cashing the Over (55) on their own.

Ohio State leads the all-time series 78-12-5, while also vacating a win in 2010. The Buckeyes have won 27 meetings in a row dating back to 1991, including last season’s 56-14 romp at “The Shoe.” Ohio State won the last trip to “The Rock” by a 54-7 count on Oct. 23, 2021.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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