Buffalo Bills at Chicago Bears odds, picks and predictions

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The Buffalo Bills (1-1) visit the Windy City on Saturday to take on the Chicago Bears (1-1) in Week 3 preseason action. Kickoff from Soldier Field is at 1 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around the Bills vs. Bears odds, and make our expert NFL picks and predictions.

Buffalo lost 27-15 in its Week 2 preseason game vs. the Pittsburgh Steelers. It was a sloppy game from Buffalo all around as the Bills committed 13 penalties and backup QB Matt Barkley threw 3 INTs. QB Josh Allen and the starting offense played briefly, but were unable to put up any points. Allen went 7-for-10 for 64 yards.

Coach Sean McDermott said he plans to play the starters vs. Chicago, but that they won’t see extensive action.

Chicago lost 24-17 to the Indianapolis Colts in its 2nd preseason game. The Bears sat most of their starters in that game including starting QB Justin Fields, but QBs Nathan Peterman and Tyson Agent were impressive in the time they saw vs. the Colts.

Coach Matt Eberflus has not yet committed to playing the starters vs. Buffalo, but all indications are that he will.

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Bills at Bears odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 7:06 p.m. ET.

Moneyline (ML): Bills -145 (bet $145 to win $155) | Bears +120 (bet $100 to win $120)
Against the spread (ATS): Bills -2.5 (-110) | Bears +2.5 (-110)
Over/Under (O/U): 39 (O: -110 | U: -110)

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Bill at Bears picks and predictions

Prediction

Bills 26, Bears 24

Moneyline

LEAN BILLS (-145).

I like the Bills to win here although they have looked sloppy in the preseason so far, even when the starters are in, so that does cause some concern. I also am not a huge fan of such a risky bet at (-145) in a game that feels like a toss-up to me. The Bills should be a decently safe lean, but if you don’t want to bet the juice then play the spread and/or O/U instead.

Against the spread

BET BEARS +2.5 (-110).

The Bears have gotten solid production from 2 of their backup QBs and I expect that to play a role in the 2nd half of this game, when the starters will likely be sitting. The Bills have been plagued by penalties, racking up 21 in their 2 preseason games, and Barkley looked bad vs. Pittsburgh. This is your best bet for this game.

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Over/Under

LEAN OVER 39 (-110).

Both of these teams have proven that they can put up 20+ points, and even in their losses they were able to score 15+. If the starters do play significant time for both teams then I expect the over to be a very safe bet, and even with the backups in the Over should be safe here.

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