Oakland Athletics at St. Louis Cardinals odds, picks and predictions

Analyzing Monday’s Oakland Athletics at St. Louis Cardinals odds and lines, with MLB expert picks, predictions and best bets.

The Oakland Athletics (33-85) and St. Louis Cardinals (52-66) open a 3-game set at Busch Stadium Monday. First pitch is at 7:45 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Athletics vs. Cardinals odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 when Athletics won 4-0

The A’s were swept by the Washington Nationals over the weekend, and they have dropped 5 of the last 6. They are 8-22 over the last 30 games and have the worst record in baseball.

The Cards had a rare day off Sunday and enter this one 5-5 over the last 10 games. They sit 12 1/2 games out in the NL Central and 9 1/2 out of a Wild-Card spot. So they aren’t totally out of it, but the playoffs are pretty unlikely.

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Athletics at Cardinals projected starters

LHP JP Sears vs. RHP Miles Mikolas

Sears (2-9, 4.23 ERA) makes his 24th start. He has a 1.12 WHIP, 2.1 BB/9 and 8.4 K/9 in 125 2/3 innings.

  • Last start: Loss, 4 IP, 4 ER, 9 H, 1 BB, 6 K Tuesday in 6-1 loss against the Texas Rangers
  • Home/road splits: 2-5, 3.82 ERA, 1.08 WHIP, 8.7 K/9 in 13 road starts vs. 0-4, 4.75 ERA, 1.18 WHIP, 8.0 K/9 in 10 home starts

Mikolas (6-8, 4.20 ERA) makes his 26th start. He has a 1.28 WHIP, 1.7 BB/9 and 6.3 K/9 in 141 1/3 innings.

  • Last start: Loss, 7 IP, 2 ER, 8 H, 0 BB, 5 K Tuesday in 4-2 loss against Tampa Bay Rays
  • Home/road splits: 2-4, 4.78 ERA, 1.25 WHIP, 7.3 K/9 in 12 starts vs. 4-4, 3.72 ERA, 1.31 WHIP, 5.5 K/9 in 13 road starts

Athletics at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:04 a.m. ET.

  • Moneyline (ML): Athletics +170 (bet $100 to win $170) | Cardinals -210 (bet $210 to win $100)
  • Run line (RL)/Against the spread (ATS): Athletics +1.5 (-115) | Cardinals -1.5 (-105)
  • Over/Under (O/U): 8.5 (O: -120 | U: +100)

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Athletics at Cardinals picks and predictions

Prediction

Cardinals 4, Athletics 2

Moneyline

There is no way you should ever bet -210 on anything to do with the Cardinals. They have been wildly inconsistent and underperformed all season and can’t be trusted on a nightly basis.

PASS.

Run line/Against the spread

The A’s are 27-32 on the RL on the road, which is pretty good considering their overall record. The problem I have is they have scored 2 runs or fewer in 7 of 10 games. On the flip side, the Cards are just 25-33 on the RL at home.

Head to the Win/Total section and take the CARDINALS AND UNDER 9.5 (+160). That will provide a better margin for error at solid plus-money.

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Over/Under

The Athletics are 5-5 O/U over the last 10, and the Cardinals are 4-6. There is very little head-to-head data to roll with here, but at this point we know what these teams are. St. Louis doesn’t play lefties particularly well at 13-16. Oakland is just 13-27 in interleague play. The Under has cashed at this same total in Mikolas’ last 2 starts.

LEAN UNDER 8.5 (+100).

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