Seattle Mariners at Houston Astros odds, picks and predictions

Analyzing Friday’s Seattle Mariners at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The Seattle Mariners (43-43) and Houston Astros (49-39) play the 2nd game of a 4-game set Friday at Minute Maid Park. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Mariners vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: Mariners lead 3-1

The Mariners won 5-1 as -138 favorites in the series opener on Thursday. Seattle has won 5 of its last 6 games and is 4th in the AL West, 7 games behind the division-leading Texas Rangers.

The Astros have won 7 of their last 9 games and 6 of those wins were by multiple runs. Houston is 2 games back of the Rangers for the lead in the division.

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Mariners at Astros projected starters

RHP Luis Castillo vs. RHP Hunter Brown

Castillo (5-6, 3.05 ERA) makes his 18th start. He has a 1.07 WHIP, 2.5 BB/9 and 10.2 K/9 in 100 1/3 innings.

  • Last outing: No-decision, 6 IP, 6 R (4 ER), 7 H, 0 BB, 6 K in a 7-6 home win vs. Tampa Bay Rays Sunday
  • Has allowed more than 3 ER in just 1 of his last 8 starts
  • Career vs. Astros: 1-0, 4.15 ERA (13 IP, 6 ER), 7 H, 1 HR, 7 BB, 12 K in 2 starts

Brown (6-5, 3.76 ERA) makes his 17th start. He has a 1.25 WHIP, 3.0 BB/9 and 10.2 K/9 in 91 innings.

  • Last outing: Loss, 4 IP, 3 ER, 10 H, 0 BB, 6 K in 5-2 loss at Rangers Saturday
  • Has allowed more than 3 ER in just 1 of his last 5 starts
  • First career start vs. Mariners

Mariners at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:05 p.m. ET.

  • Moneyline (ML): Mariners -110 (bet $110 to win $100) | Astros -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners -1.5 (+155) | Astros +1.5 (-190)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Mariners at Astros picks and predictions

Prediction

Astros 5, Mariners 4

Moneyline

Houston is 4-1 in its last 5 home games and should bounce back after a bad loss in the series opener.

Seattle is just 3-8 in its last 11 games after allowing 2 or fewer runs in its previous contest, and Castillo had 1 of his worst starts of the season last time out.

BET ASTROS (-110).

Run line/Against the spread

Houston +1.5 (-190) should hit, but there’s no need to pay the higher price on the run line when the Astros should win straight up. Bet the ML and/or the total instead.

PASS.

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Over/Under

The Over is 6-2 in Houston’s last 8 games after a loss and 6-2 in its last 8 at home vs. right-handed starters.

The Over has hit in 4 of Seattle’s last 5 games vs. AL West teams and should cash again Friday, especially if Castillo has another below-average performance.

BET OVER 7.5 (+100).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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