Cleveland Guardians at Chicago White Sox odds, picks and predictions

Analyzing Wednesday’s Cleveland Guardians at Chicago White Sox odds and lines, with MLB expert picks, predictions and best bets.

The Cleveland Guardians (19-22) and Chicago White Sox (15-28) meet Wednesday for the 2nd game of a 3-game series. First pitch from Guaranteed Rate Field is set for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 1-0

Cleveland had a 2-game win streak snapped Tuesday with an 8-3 as a -121 road favorite in the series opener. Chicago broke a scoreless tie with 6 runs in the bottom of the 5th inning. The White Sox are 2-4 in their last 6 games overall and 2-2 in their last 4 home games; Chicago is 8-12 at home on the season.

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Guardians at White Sox projected starters

RHP Peyton Battenfield vs. RHP Mike Clevinger

Battenfield (0-4, 4.45 ERA) makes his 6th start and 7th appearance. He has a 1.19 WHIP, 3.3 BB/9 and 7.4 K/9 through 30 1/3 IP.

  • Last outing: Loss, 6 IP, 4 ER, 7 H, 0 BB, 4 K, in a 5-0 home loss vs. Detroit Tigers last Wednesday
  • First career start vs. White Sox

Clevinger (2-3, 4.79 ERA) makes his 9th start. He has a 1.43 WHIP, 3.9 BB/9 and 7.6 K/9 through 41 1/3 IP.

  • Last outing: No-decision, 6 IP, 3 ER, 3 H, 2 BB, 2 K, in a 4-3 road loss vs. Kansas City Royals Thursday
  • Career vs. Cleveland: 0-1 4.22 ERA (10 2/3 IP, 5 ER), 6 H, 2 HR, 4 BB and 8 K across 2 starts

Guardians at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:33 a.m. ET.

  • Moneyline (ML): Guardians -105 (bet $105 to win $100) | White Sox -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians -1.5 (+155) | White Sox +1.5 (-190)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Guardians at White Sox picks and predictions

Prediction

Guardians 5, White Sox 2

Moneyline

BET GUARDIANS (-105).

The White Sox are a bad home team and the Guardians are a solid road team, with a 10-10 road record on the season. Recent matchups between these teams have been fairly even, with each team winning 5 of the last 10 meetings. However, the Guardians are 3-1 in the last 4 meetings and have a slight edge heading into Wednesday.

Run line/Against the spread

LEAN GUARDIANS -1.5 (+155).

This is your riskiest bet for this game. Only 1 of the last 10 meetings between these teams finished with a 1-run margin and the Guardians are a lean to cover. However, the White Sox have already proven they can beat the Guardians this season so this is a hard wager to get a good feel for.

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Over/Under

BET UNDER 9 (-115).

The Under is 5-0 in Cleveland’s last 5 Wednesday games and 5-0 in Battenfield’s 5 career starts on grass. The Under is also 6-2-2 in Cleveland’s last 10 overall.

The Under is 5-1-1 in Chicago’s last 7 game 2s and 4-1 in their last 5 games overall.

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