Chicago White Sox at Houston Astros odds, picks and predictions

Analyzing Friday’s Chicago White Sox at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The Chicago White Sox (1-0) take on the Houston Astros (0-1) Friday in the 2nd game of a 4-game season-opening series at Minute Maid Park. First pitch is at 8:10 p.m. ET (MLB Network). Let’s analyze Tipico Sportsbook’s lines around the White Sox vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: White Sox lead 1-0

The White Sox defeated the Astros 3-2 on Thursday with RHP Dylan Cease  allowing only 1 ER while fanning 10 in 6 1/3 IP. RHP Reynaldo Lopez got the save as Chicago looks to replace closer Liam Hendriks, who is undergoing cancer treatment.

The World Series champions got a solid outing from LHP Framber Valdez on Thursday with 4 K and 0 ER in 5 IP while OF Yordan Alvarez homered in the 9th inning.

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White Sox at Astros projected starters

RHP Lance Lynn vs. RHP Cristian Javier

Lynn was 8-7 in 21 starts in 2022 with a 3.99 ERA, 1.13 WHIP, 1.4 BB/9, and 9.2 K/9 in 121 2/3 IP.

  • Recorded at least 6 IP in 13 of his 21 starts last year
  • His 3.99 ERA last season was his highest since 2018

Javier was 11-9 in 25 starts last season with a 2.54 ERA, 0.95 WHIP, 3.1 BB/9, and 11.7 K/9 in 148 2/3 IP.

  • Tallied 6-plus K’s in his final 6 starts of 2022
  • Tied for 8th in ERA and had the 3rd-best K/9 among starting pitchers despite lacking IP to qualify for the league leaders

White Sox at Astros odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:07 a.m. ET.

  • Moneyline (ML): White Sox +130 (bet $100 to win $130) | Astros -150 (bet $150 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-160) | Astros -1.5 (+140)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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White Sox at Astros picks and predictions

Prediction

Astros 4, White Sox 2

Moneyline

AVOID.

Unless you believe the White Sox can start the season 2-0 over the Astros, then I wouldn’t wager on the moneyline in this game. I’d be comfortable taking Houston’s moneyline at -140 odds or better.

Run line/Against the spread

ASTROS -1.5 (+130)

Houston is looking to avoid starting the season with 2 straight losses and while they certainly miss 2B Jose Altuve at the front of their lineup, they still possess a dangerous group of hitters.

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Over/Under

BET UNDER 7.5 (-105).

Lynn is poised to bounce back in 2023 and Javier is someone I believe is capable of winning the AL Cy Young award this season. There have been under 8 runs scored in 6 of the last 7 meetings between these teams.

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