The Dallas Cowboys (13-5) and San Francisco 49ers (14-4) meet Sunday in the Divisional Round of the NFL playoffs. Kickoff from Levi’s Stadium is set for 6:30 p.m. ET (FOX). Below, we analyze Tipico Sportsbook’s lines around the Cowboys vs. 49ers odds, and make our expert NFL picks and predictions.
The most recent meeting between these 2 teams was last postseason during Wild Card Weekend Jan. 16, 2022. The 49ers won 23-17 as 3.5-point road underdogs. WR Deebo Samuel rushed for a 26-yard TD in the 3rd quarter that gave San Francisco a comfortable 2-possession lead. He finished with 72 rushing yards (and 38 receiving), while RB Elijah Mitchell ran for 96 yards with a score.
The Cowboys, the NFC’s 5th seed, advanced here after covering the spread as 2.5-point favorites with a 31-14 win at the Tampa Bay Buccaneers Wild Card Weekend. QB Dak Prescott threw 4 TDs and ran for a 5th score as Dallas defeated QB Tom Brady for the 1st time in franchise history.
The 49ers, the NFC’s No. 2 seed, covered as 10-point home favorites on last week in a 41-23 win vs. the Seattle Seahawks. QB Brock Purdy finished with 3 passing TDs and ran for another, becoming the 1st rookie QB to account for 4 TDs in a postseason game.
FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+
Cowboys at 49ers odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:30 p.m. ET.
- Moneyline (ML): Cowboys +180 (bet $100 to win $180) | 49ers -210 (bet $210 to win $100)
- Against the spread (ATS): Cowboys +4 (-110) | 49ers -4 (-110)
- Over/Under (O/U): 46.5 (O: -111 | U: -109)
Catch the excitement and bet with Tipico
Double Down, Ohio! Deposit $200, Get $250. Bet now!
In Colorado and New Jersey, claim your 100% Deposit Match up to $250 now. Bet now! 21+, see Tipico.com for Terms and Conditions.
Cowboys at 49ers key injuries
Cowboys
- S Jayron Kearse (knee) questionable
- OL Jason Peters (hip) out
49ers
- QB Jimmy Garoppolo (foot) out
Play our free daily Pick’em Challenge and win! Play now!
Cowboys at 49ers picks and predictions
Prediction
49ers 23, Cowboys 20
Moneyline
PASS.
The 49ers (-210) should be able to pull out the win, but betting 2.1 times the potential profit is a little expensive considering Purdy may be due for a letdown after such an impressive rookie campaign. Prescott should be the more reliable QB in this spot, but the Cowboys may struggle to put up a lot of points vs San Francisco’s No. 2 ranked total defense.
Against the spread
BET COWBOYS +4 (-110).
The Cowboys, as a franchise, may have turned a corner after defeating Brady for the 1st time in history. Dallas won a postseason road game for the 1st time in 30 years and should be able to carry that momentum into Sunday’s matchup. Purdy has been impressive for the 49ers, but Dallas’ defense is 1st in takeaways and should make it difficult for the rookie to win his 2nd postseason game. TAKE THE POINTS.
Over/Under
BET UNDER 46.5 (-109).
Dallas’ defense should continue to look dominant Sunday as the Under is 5-1 in the Cowboys’ last 6 January games. The Over is 4-0 in San Francisco’s last 4 games, but Purdy should regress toward the mean after a historic showing in his postseason debut. Dallas and San Francisco are 1st and 2nd, respectively, in takeaways per game and should make this game uncomfortable for both quarterbacks.
Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!
If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.
Follow Corey Scott on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Access more NFL coverage:
BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire
[lawrence-newsletter]
[lawrence-auto-related count=3 category=1367]