Los Angeles Chargers at Denver Broncos odds, picks and predictions

Analyzing Sunday’s Los Angeles Chargers at Denver Broncos odds and lines, with expert NFL picks, predictions and best bets.

The Los Angeles Chargers (10-6) visit the Denver Broncos (4-12) Sunday in Week 18 at Empower Field at Mile High. Kickoff is scheduled for 4:25 p.m. ET (CBS). Below, we analyze Tipico Sportsbook’s lines around the Chargers vs. Broncos odds, and make our expert NFL picks and predictions.

The Chargers cruised to a 31-10 win over the Los Angeles Rams in Week 17 to cover as 6.5-point favorites at home. Los Angeles enters Week 18 on a 4-game winning streak. A loss by the Baltimore Ravens at the Cincinnati Bengals Sunday in a 1 p.m. ET kickoff could allow them to rest its starters.

The Broncos lost 27-24 at the Kansas City Chiefs in Week 17 but covered as 13.5-point underdogs. Denver has had a disappointing season, but the team will look to finish on a positive note Sunday.

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Chargers at Broncos odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:09 a.m. ET.

  • Moneyline (ML): Chargers +140 (bet $100 to win $140) | Broncos -160 (bet $160 to win $100)
  • Against the spread (ATS): Chargers +3 (-106) | Broncos -3 (-114)
  • Over/Under (O/U): 39.5 (O: -111 | U: -109)

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Chargers at Broncos key injuries

Chargers

  • None

Broncos

  • OL Calvin Anderson (ankle) out
  • WR Kendall Hinton (chest, foot) out
  • DL D.J. Jones (knee) out
  • CB Damarri Mathis (concussion) questionable
  • TE Eric Saubert (knee) questionable
  • TE Eric Tomlinson (ankle) questionable
  • OL Billy Turner (back) questionable

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Chargers at Broncos picks and predictions

Prediction

Chargers 24, Broncos 20

Moneyline

I’ll take the CHARGERS (+125) to win if they play most of their starters. The issue is that if the Ravens lose to the Bengals earlier in the day — Cincy is a 9-point home favorite — then the Chargers can rest starters if they want as they’ll be locked into the AFC’s No. 5 seed.

So, it may be wise to wait until the end of the Ravens-Bengals game to wager on this one.

Against the spread

If the Chargers have something to play for, then LOS ANGELES +3 (-106) is an enticing bet. Unless you’re confident in the Chargers either winning or keeping it close, keep tabs on the status of the starters on Sunday.

The Chargers are 3-0-1 ATS in their last 4 games overall.

Over/Under

OVER 39.5 (-111) is another bet I like if the Chargers are running out their starters in Week 18. If Los Angeles opts to rest players because the Ravens lost, I’d side with the Under as the Chargers won’t be looking to throw as often.

The Over is 4-0 in the last 4 games for the Broncos. On top of that, the Over is 6-2 in the last 8 meetings between the Chargers and the Broncos when the game is in Denver.

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