The NFL’s Week 14 schedule wraps up with the New England Patriots (6-6) visiting the Arizona Cardinals (4-8) on Monday Night Football at 8:15 p.m. ET from State Farm Stadium (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Patriots vs. Cardinals odds, and make our expert NFL picks and predictions.
The Patriots enter on a 2-game skid, most recently falling as 3.5-point home underdogs to the Buffalo Bills 24-10 in the Week 13 Thursday night game.
The Cardinals are coming off their bye week. They also are on a 2-game slide after suffering a 25-24 heartbreaking defeat on a last-minute TD and 2-point conversion by the Los Angeles Chargers in Week 12. At least the Cardinals covered the spread as 2.5-point dogs, but they are 1-4 straight up and 2-3 ATS in their last 5 games.
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Patriots at Cardinals odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 7:42 p.m. ET.
- Moneyline (ML): Patriots -125 (bet $125 to win $100) | Cardinals +105 (bet $100 to win $105)
- Against the spread (ATS): Patriots -2.5 (-108) | Cardinals +2.5 (-112)
- Over/Under (O/U): 43.5 (O: -111 | U: -109)
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Patriots at Cardinals key injuries
Patriots
- OL Trent Brown (illness) questionable
- OL Yodny Cajuste (back, calf) questionable
- RB Damien Harris (thigh) doubtful
- WR Jakobi Meyers (concussion) out
- CB Jalen Mills (groin) out
- OL Isaiah Wynn (foot) out
Cardinals
- DL Zach Allen (illness) questionable
- OL Rashaad Coward (chest) out
- WR Rondale Moore (groin) out
- CB Byron Murphy (back) out
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Patriots at Cardinals picks and predictions
Prediction
Cardinals 24, Patriots 20
Moneyline
The Cardinals have only one win at home this season and only 1 win in their last 5 games. However, they did look competitive on offense for the first time in a while in their loss to the Chargers.
The Patriots are 7th-best in both yards and points allowed, giving up 311.8 yards and 18.8 points per game (PPG). However, they have been hot and cold. In their 6 wins, opponents score only 8.7 PPG. In their 6 losses, opponents have scored 29.0 PPG. They have not won a game with opponents scoring more than 17 points.
If the Cardinals are able to move the ball on offense like they did against the Chargers, they can win this game.
QB Kyler Murray’s mobility will wreak havoc on New England’s defense, which allowed Chicago Bears QB Justin Fields to rush for 82 yards and a touchdown.
I like the upset here. BET CARDINALS (+105).
Against the spread
The Patriots are 6-5-1 ATS, while the Cardinals are 6-6 ATS, covering the spread twice in losses.
The Cardinals also have covered the spread in 2 of their last 3 games.
All the reasons noted to convince you to bet the Cardinals on the moneyline are the same reasons why you should bet the Cardinals to cover the spread.
But if you are going to pick one or the other, the moneyline is better because of the positive line.
If you fear the possible 1-point loss like the Cardinals had in their last game, bet the spread, but I say go with the moneyline and PASS on the spread.
Over/Under
The Cardinals’ last 6 games have all had 44 or more total points.
Four of the Pats’ 6 losses had 44 or more points.
BET OVER 43.5 (-111).
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