New York Yankees at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s New York Yankees at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The New York Yankees (70-36) and St. Louis Cardinals (57-48) open a 3-game interleague series Friday. First pitch from Busch Stadium is set for 8:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Yankees vs. Cardinals odds with MLB picks and predictions.

Season series: first meeting since 2017

The Yankees are a pedestrian 12-15 since July 3. New York owns a 4.51 road ERA over that stretch.

The Cardinals have won 4 games in a row and 6 of their last 7. St. Louis is 8-2 with an .863 OPS over its last 10 games at Busch Stadium.

PLAY: Free, daily sports pick’em contests. Play now!

Yankees at Cardinals projected starters

LHP Nestor Cortes vs. RHP Dakota Hudson

Cortes (9-3, 2.53 ERA) has notched a 1.02 WHIP, 2.0 BB/9 and 9.4 K/9 through 106 2/3 IP in 19 starts.

  • Owns a 3.65 ERA across his last 7 starts.
  • Has benefited from a .262 batting average on balls in play and has held foes to a .171 batting average (with a .194 BABIP) in high-leverage situations.

Hudson (6-6, 4.10 ERA) is also making his 20th start. He’s posted a 1.36 WHIP, 3.9 BB/9 and 4.8 K/9 through 101 IP.

  • Has struggled on the road (5.26 ERA) but owns a 2.98 ERA and 1.15 WHIP at home.
  • Making his second start off the IL after missing 1 turn since the All-Star break. Returned from a neck injury Saturday and allowed 2 runs in 4 1/3 IP at the Washington Nationals.

Yankees at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:33 a.m. ET.

  • Money line: Yankees -160 (bet $160 to win $100) | Cardinals +130 (bet $100 to win $130)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (+105) | Cardinals +1.5 (-130)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Yankees at Cardinals picks and predictions

Prediction

Yankees 6, Cardinals 4

Money line

Not much to like about either price here: AVOID.

Win your fantasy baseball league with BaseballHQ.com. For decades, BHQ has been helping players just like you win! Use the couple code SBW22 for 20% OFF full-season subscription. New customer offer; expires 8/31/2022. Subscribe today and start winning!

Run line/Against the spread

The lean here is a slight one, but it’s on the YANKEES -1.5 (+105).

Hudson is a bit of a question mark, having pitched just once since July 14. The Redbirds played a Thursday twin bill while the Yanks were off, and the New York bullpen is in better shape for this opener.

Over/Under

Both starters have some expected-ERA figures that favor an Over here. Hudson has experienced a drop in velocity of late and negotiated some hard-hit outs in his last start.

On a warm and humid night in St. Louis, BACK THE OVER 8.5 (-110).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1372]

[mm-video type=playlist id=01fb7dafw2b08817yr player_id=none image=https://sportsbookwire.usatoday.com/wp-content/plugins/mm-video/images/playlist-icon.png]