Best bets in the South Region of the 2022 NCAA Men’s Tournament

Who prevails in a potential matchup between Tennessee and Villanova?

It remains to be seen how healthy Arizona will be for the start of the 2022 NCAA Tournament, as the Wildcats manage the ankle injury to starting point guard Kerr Kriisa. But there’s no denying that the top seed in the South Region still remains a heavy favorite to go on a deep run regardless of the news there.

The bigger question marks are lower seeded teams like No. 11 Michigan and whether the Wolverines can knock off No. 6 Colorado State. Or what happens between No. 8 Seton Hall and No. 9 TCU. Or better yet, will Tennessee’s snub as a No. 2 seed come back to bite it in a potential matchup against No. 2 Villanova.

The South Region has some enticing matchups but only a few teams truly inspire confidence in their ability to go deep.

Here’s a look at the best bets in the South Region, with odds via Tipico Sportsbook.