Despite the Buffalo Bills losing to the Jacksonville Jaguars two weeks ago, they were still two-touchdown favorites heading into last week against the New York Jets.
When it was all said and done, the Bills (6-3) blew that spread out of the water in a 45-17 win.
Following that, in little surprise, Buffalo is favored again in Week 11.
At home against the Indianapolis Colts (5-5) next weekend, the Bills have opened as 7.5-point favorites. That line comes to us via Tipico Sportsbook (access USA TODAY Sports’ betting odds for a full list).
This one isn’t the simplest ones to predict, though.
While the Bills blew out the Jets last week, the Colts did cough up a big lead against the Jaguars, hanging on 23-17.
Then again… they did beat the Jags unlike Buffalo…
And making picking this game even more difficult might be the recency bias. In the Colts’ last five games? They have won four of those. They’re pretty hot right now.
But in the direct recent history between these two sides, in last season’s AFC postseason, Buffalo beat Indy 27-24.
However, if the spread isn’t your thing, we at least have some other numbers to consider: The over/ under has opened at 49.5.
The moneyline sits at Bills (-330) and Colts (+265).
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