Iowa State at Baylor odds, picks and prediction

Analyzing Saturday’s Iowa State Cyclones at Baylor Bears odds and lines, with college football expert picks, predictions and best bets.

The 14th-ranked Iowa State Cyclones (2-1, 0-0 Big 12) and Baylor Bears (3-0, 1-0) meet Saturday at McLane Stadium in Waco, Texas. Kickoff is scheduled for 3:30 p.m. ET. Below, we look at the Iowa State at Baylor odds and lines, and make our expert college football picks, predictions and bets.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

The Cyclones fell to rival Iowa 27-17 Sept. 11. They got back on track with a 48-3 road rout of a very bad UNLV team for their first cover against the spread this season. They were 32-point road favorites and the Under in their games improved to a perfect 3-0.

The Bears started out a bit on the shaky side, edging Texas State 29-20 on the road in their season opener Sept. 4. They have since rebounded, blasting FCS Texas Southern 66-7 at home before blasting Kansas on the road by a 45-7 count.

Iowa State at Baylor odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 9:13 a.m. ET.

  • Money line: Iowa State -290 (bet $290 to win $100) | Baylor +225 (bet $100 to win $225)
  • Against the spread (ATS): Iowa State -6.5 (-125) | Baylor +6.5 (+102)
  • Over/Under (O/U): 46.5 (O: -117 | U: -103)

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Iowa State at Baylor odds, lines, picks and predictions

Prediction

Iowa State 26, Baylor 17

Money line

Iowa State (-290) will cost you nearly three times your potential return. That’s risky business on the road, especially against an unbeaten Baylor side.

AVOID.

Against the spread

IOWA STATE -6.5 (-125) is a decent play on the road as it looks to build upon its first cover of the season. Baylor will have its hands full trying to solve the nation’s stingiest defense. That will be the difference here.

Iowa State QB Brock Purdy had a wake-up call in the loss to Iowa, while the offense really found some confidence at UNLV. The Cyclones will head down to Waco and edge Baylor, pulling away in the fourth quarter.

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Over/Under

UNDER 46.5 (-103) is the slight lean in this play as both Baylor and Iowa State have put up tremendous numbers on defense. Both offenses will not find the type of success they’ve seen against weaker non-conference foes.

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