The Denver Broncos and New York Giants meet Sunday at MetLife Stadium. Kickoff is scheduled for 4:25 p.m. ET and the game is televised on FOX. Below, we look at the Broncos vs. Giants odds and lines, and make our best NFL picks, predictions and bets.
The Broncos head to the Eastern Time Zone where they had a ton of success a season ago. Denver went 3-2 straight up and 4-1 against the spread in five trips east of the Mississippi River, while going 2-9 SU and 5-6 ATS elsewhere.
The Giants had a difficult time against AFC teams last season, going just 1-3 SU and 0-4 ATS. New York also hit the Under in all four games against AFC opponents in 2020. The G-Men are just 3-9 ATS over the last three seasons against AFC foes.
Also see: NFL team win totals
Broncos at Giants odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 12:50.m. ET.
- Money line: Broncos -160 (bet $160 to win $100) | Giants +130 (bet $100 to win $130)
- Against the spread (ATS): Broncos -2.5 (-135) | Giants +2.5 (+110)
- Over/Under (O/U): 41.5 (O: -108 | U: -112)
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Broncos at Giants key injuries
Broncos
- LB Bradley Chubb (ankle) questionable
Giants
- RB Saquon Barkley (knee) questionable
- TE Evan Engram (calf) out
- DB Adoree’ Jackson (ankle) questionable
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Broncos at Giants odds, lines, predictions and picks
Prediction
Broncos 26, Giants 17
Money line
The BRONCOS (-160) are moderate favorites, and not a bad option on the money line if you just want to pick a winner and not worry about the point spread.
The Giants haven’t had a lot of success against the AFC in recent seasons, and the fact Barkley is dinged up and Engram is out does not help matters. New York could get off to a slow start yet again.
Also see: Week 1 staff picks
Against the spread
BRONCOS -2.5 (-135) is worth a small-unit play, as Denver seemed to enjoy traveling last season. Most of their best games were away from home.
QB Teddy Bridgewater makes his team debut and has a solid stable of receivers. The Giants aren’t nearly as deep. Engram would’ve been super helpful for QB Daniel Jones, but he is already ruled out. That’s bad news for the home side, and it gets worse if Barkley is ruled inactive.
Over/Under
The lean is to the OVER 41.5 (-108), ever so slightly.
The concern is with the Giants side, again, if Barkley cannot play. Bridgewater and the Broncos offense should be much better than last season, and they should do enough to inch this one Over the finish line for total bettors.
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