Cincinnati Red at San Diego Padres odds, picks and prediction

Analyzing Friday’s Cincinnati Reds at San Diego Padres odds and lines, with MLB picks and predictions.

The Cincinnati Reds (35-32) face the San Diego Padres (39-32) in the second game of a four-game series Friday night. First pitch is scheduled for 10:10 p.m. at Petco Park. Let’s analyze BetMGM Sportsbook‘s lines around the Reds vs. Padres odds with MLB picks and predictions.

RHP Tony Santillan is the projected starting pitcher for the Reds. He is making just his second MLB start after allowed 1 ER on 5 H and 4 BB with 5 K over 4 2/3 IP against the Colorado Rockies Sunday.

The Reds picked up a 6-2 win in Santillan’s debut.

RHP Chris Paddack is the projected starting pitcher for the Padres. He is 3-5 with a 4.14 ERA, 1.16 WHIP, 8.7 K/9 and 2.0 BB/9 in 58 2/3 IP over 12 starts.

The Padres are 7-5 with Paddack on the mound. He has had quality starts in four of his last five appearances.

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Reds at Padres odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:30 a.m. ET.

  • Money line: Reds +180 (bet $100 to win $180) | Padres -225 (bet $225 to win $100)
  • Against the spread/ATS: Reds +1.5 (-110) | Padres -1.5 (-110)
  • Over/Under: 8.5 (O: -120 | U: +100)

Prediction

Reds 4, Padres 3

Money line (ML)

The Reds had their six-game winning streak snapped Thursday night with their 6-4 loss to the Padres in the series opener. They are 19-16 on the road this season.

The Padres are 22-14 at Petco Park. Before Thursday night’s win over the Reds, they had lost seven of their previous nine games. They are 2-3 at home when Paddack starts.

Give a slight LEAN to REDS (+180).

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Run line/Against the spread (ATS)

The Reds are 31-36 ATS overall this season and 18-17 ATS on the road. They covered the spread in 11 of their last 14 games.

The Padres are 17-19 ATS at home this season but covered the spread in only five of their last 18 games.

Expecting an outright win by the Reds, you can give yourself a one-run cushion with your bet. Take the REDS +1.5 (-110).

Over/Under (O/U)

The Reds have the third-highest Over percentage in the league at 60.9%. Five of their last eight games went over the projected total.

However, only 41.7% of the Padres’ home games have hit the Over.

Take UNDER 8.5 (+100).

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