The Tennessee Titans (6-2) will try to keep their AFC South lead with a win when they host the Indianapolis Colts (5-3) on Thursday Night Football. The two teams will be playing the first of two games in a three-week stretch with the rematch set for Week 12 in Indianapolis. Below, we preview the Colts-Titans betting odds and lines and make our NFL picks and predictions.
The TNF kickoff will be at 8:20 p.m. ET at Nissan Stadium.
Colts at Titans: Betting odds, spread and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 3:34 p.m. ET.
- Money line: Colts +115 (bet $100 to win $115) | Titans -134 (bet $134 to win $100)
- Against the spread/ATS: Colts +2 (-110) | Titans -2 (-110)
- Over/Under: 48.5 (O: -110 | U: -110)
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Colts at Titans: Game notes
- The Titans snapped a mini-two-game losing skid with a 24-17 home win over the Chicago Bears last week. The Colts had a two-game win streak end with a 24-10 home loss against the Baltimore Ravens.
- Tennessee is 4-1 straight up and 3-2 against the spread at home. Indianapolis is 2-2 SU and ATS as the road team.
- The Colts are underdogs for the first time in four games. They’ve gone 2-1 SU but 1-2 ATS in their last three contests. The Titans are favored for a fifth straight game and eighth time in nine games this season. They’re 4-2-1 ATS in those games.
- Tennessee beat Indianapolis 31-17 on Dec. 1, 2019, to end a three-game winning streak for the Colts in the head-to-head series.
- The Titans offense goes through RB Derrick Henry, who has 843 rushing yards and 8 touchdowns on the ground this season. The Colts rank second in the NFL with just 3.3 rushing yards allowed per attempt.
- Tennessee leads the NFL with a turnover differential of plus-10; Indianapolis has a differential of plus-4. The Colts have 9 giveaways to the Titans’ 4, including 7 interceptions from QB Philip Rivers.
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Colts at Titans: Key injuries
Colts
- TE Mo Alie-Cox (knee) questionable
- TE Jack Doyle (concussion) out
Titans
- DE Jadeveon Clowney (knee, illness) questionable
- WR Adam Humphries (concussion) questionable
- RT Dennis Kelly (knee) questionable
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Colts at Titans: Odds, betting lines, predictions and picks
Prediction
Titans 24, Colts 20
Money line (?)
The TITANS (-134) would stay on top of the division with a win. Tennessee played a good defense in Chicago last weekend and still managed to put up 24 points.
The Titans allow 25.1 points per game to the Colts’ 20.0, but the Tennessee defense is very opportunistic and will be able to force Rivers into some turnovers and pad its league-best turnover differential.
Against the spread (?)
Get better value on the TITANS -2 (-110) by backing them to win by at least 3 points. Each of their last three victories came by a margin of at least 6 points after each of their first three games was decided by 3 or fewer points.
Over/Under (?)
Take the UNDER 48.5 (-110) in a very important division game. The two will meet again in Week 12, and it should be expected to be the higher-scoring game of the two as the Colts and Titans feel each other out in Nashville.
Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.
Also see:
- GM Ballard ‘expect(s) big things from’ RB Taylor in second half (Colts Wire)
- Titans’ midseason awards: Who’s the MVP? (Titans Wire)
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